TOC-L Total Organic Carbon Analyzer
Consisting of four models, including PC-controlled and standalone versions, the TOC-L uses Shimadzu’s 680° C combustion catalytic oxidation method to efficiently analyze all organic compounds. It features automatic sample acidification and sparging, as well as an automatic dilution function that reduces sample salinity, acidity and alkalinity. This significantly extends the use of catalysts and combustion tubes. The TOC…
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Good and reliable device, easy to use
Pharma
Software features intuitive operability and a wealth of function, reliable, easy repair, sample digestion without reagents
Review Date: 25 Mar 2022 | Shimadzu Corporation
Total Organic Carbon Analyzer in medical device industry Industry
Protein Estimation, Quantification, Medical device cleaning studies
Total Organic Carbon analyzer utilizes a catalytic oxidation combustion technique at high temperatures (the temperature raises up to 720 ºC). The CO2 generated by oxidation is measured with a Non-dispersive Infra-Red (NDIR) sensor. This equipment is the best choice equipment for the qualitative/quantitative analysis of water, protein, carbohydrate, hemoglobin etc, especially in the medical device industry. I am a satisfied user of this Shimadzu equipment.
Review Date: 16 Dec 2021 | Shimadzu Corporation
Reusable medical device simulated cleaning studies/Water testing
Protein Estimation, Quantification, Medical device cleaning studies
Shimadzu Total organic carbon analyzer (TOC-L CPH) is advanced and more accurate for quantification and as well as qualitative estimation studies. Total organic carbon analyzer (TOC-L CPH) equipment is the perfect choice for cleaning procedure development, qualitative and quantitative estimation of protein, peptide, and carbohydrate, etc. for reusable medical devices.
Review Date: 15 Nov 2021 | Shimadzu Corporation
Easy to use, quick results
Detection of residues of cleaning agent
The instrument was bought for the analysis of residues of cleaning agents for the control of pharmaceutical equipment. It was chosen as we used it before for the analysis of traces of plastics according to USP 661. Easy to use, easy to maintain (change of HCl, H3PO4, and verification of the catalysts) with one yearly maintenance, it provides quick and reliable results.
Review Date: 15 Nov 2021 | Shimadzu Corporation
The TOC analyzer facilitated our environmental monitoring projects.
Environmental monitoring
Easy-to-use equipment, applicable to a wide range of, but that requires some preparation care to avoid particulates that can clog or injector. Satisfactory value for money. Very dedicated after-sales maintenance.
Review Date: 15 Jul 2021 | Shimadzu Corporation
Best in class and market leader.
Water samples testing, pharmaceutical clenaing verification
To assure the suitability of quality of water for intended usage and verification of equipment/facility cleaning is an emerging demand in pharmaceutical world. Shimadzu's TOC analyzer provides the best support for this objective and they are a true business partner.
Review Date: 20 Mar 2021 | Shimadzu Corporation
Great instrument, very helpful for environmental analysis.
Testing DOC in environmental water samples
High quality and reproducible results. Relatively low daily/weekly maintenance. Can be complicated to troubleshoot as there are many different pathways/parts that can be the source of the problem.
Review Date: 20 Nov 2020 | Shimadzu Corporation
Best TOC money can buy.
Drinking water samples
Best TOC analyzer we have used to date. Calibrations are easy, Maintenance is a breeze. Standard recoveries are excellent, sample setup, well what else can I say.
Review Date: 16 Jun 2020 | Shimadzu Corporation
Sensitive instrument.
TOC
Very stable sensitive instrument and reasonable price for consumables.
Review Date: 12 Mar 2020 | Shimadzu Corporation
Intuitive and informative
Groundwater and Wastewater
The TOC-L is quite intuitive. This helps for the wide span of users we have, from undergraduate researchers to PhDs. The instrument can be operated with or without a PC if benchspace is crucial. The manual is one of the most informative that I have come across. About 1/3 of it is explanation of operation and theory. Standard solution prep is also outlined well. It serves as a great reference. Shimadzu’s history with this instrument means that there are many service personnel well trained in its operation and repair.
Review Date: 9 Nov 2017 | Shimadzu Corporation
Consisting of four models, including PC-controlled and standalone versions, the TOC-L uses Shimadzu’s 680° C combustion catalytic oxidation method to efficiently analyze all organic compounds. It features automatic sample acidification and sparging, as well as an automatic dilution function that reduces sample salinity, acidity and alkalinity. This significantly extends the use of catalysts and combustion tubes.
The TOC-L Series features variable syringe sizes when the sample volume is limited. High-precision mass flow controllers ensure uninterrupted carrier gas for accurate analysis. A zero-maintenance Peltier cooler used for maximum water vapor removal ensures accurate analysis. In addition, an on-board air purifier may eliminate the need for high-purity air during testing.
The optional salt kits permit 12 times more salt to be analyzed before maintenance is required. The ASI-L autosampler can use three different vial sizes for various applications, while the smaller OCT-L autosampler can use any vial size for up to 8 or 16 samples. TOC-L models can accept particulates up to 500 microns or 800 microns with the optional particulate kit. For larger particles, solids, soils and sludge, the SSM-5000 is the ideal solution. The TNM-L can be added for simultaneous TOC and Total Nitrogen analyses without increasing the size of the footprint.
TOC and TN Measurements of Seawater
For pollution control of the ocean and in the research of the ocean environment, the measurement of total organic carbon (TOC) is regarded as an important index of organic contaminants contained in seawater. At the same time, the measurement of total nitrogen (TN), which is known to cause eutrophication, is also attracting attention for environmental pollution control and in ecological research. Seawater has an NaCl content of approx. 3.5 %.
TOC System Suitability Test for Sterile Water
The United States Pharmacopeia (USP) specifies that total organic carbon (TOC) content be used for management of organic impurity values permitted in bulk purified water, water for injection, in addition to sterile purified water and sterile water for injection. According to USP, TOC analyzers to be used for sterile water must satisfy the TOC system suitability test using test water having a carbon content of 8.0 mg/L, and must also be able to detect TOC at 0.1 mg/L or less.
Introducing a New ASTM Method for the Determination of Total Nitrogen, and TKN by Calculation, in Water Samples
This whitepaper describes a new ASTM method for the determination of nitrogen levels in water samples using high temperature catalytic oxidation on a total organic carbon analyzer. ASTM D8083-16 is a new method for the determination of total nitrogen, and TKN by calculation, in water samples. The method compares favorably with the current EPA approved calculated total nitrogen in samples without interferences. ASTM D8083-16 saves laboratories time, uses less reagent and smaller sample volumes, and overcomes several known issues with current TKN and TN methods.
Total Organic Carbon Determination According to USP 643
This application note describes the determination of impurities in purified water and water for injections according to the US Pharmacopeia Total Organic Carbon (TOC) parameter. Shimadzu offers two systems that are ideally suitable for TOC determination in ultrapure water. Both types of instrument with their different oxidation methods can be used for TOC determination in accordance with the new United States Pharmacopeia USP 643.
TOC System Suitability Test for Sterile Water According to USP
According to United States Pharmacopeia (USP), Total Organic Carbon (TOC) analyzers must be able to detect TOC at 0.1 mg/L or less. This application note introduces an example of a TOC system suitability test, using the Shimadzu TOC-LCPH combustion catalytic oxidation analyzer.
TOC Monitoring Upstream of Paper Mill Wastewater Treatment Facility Using Online TOC Analyzer
At wastewater treatment facilities of various types of manufacturing plants, pollution load monitoring upstream monitoring) is becoming increasingly) important to ensure appropriate and stable operation and water pollution accident prevention. This application note presents the use of the online TOC-4200 for the continuous measurement of papermill wastewater. The TOC-4200 is a high-performance on-line TOC analyzer, based on the proven 680°C Catalyst-aided Combustion technology.
Measurement of TOC and TN in Marine Water Algae Culture Solution
The culturing of microalgae in various types of non-edible biomass has been receiving considerable attention in recent years. Various nutrients, such as nitrogen compounds, are added to these types of microalgae cultures but these must be managed within an appropriate range. This application note describes the use of Shimadzu’s TOC-L Series Combustion Type Total Organic Carbon Analyzer in the direct measurement of the total organic carbon (TOC) and total nitrogen (TN) content in high-salt samples such as seawater, without requiring dilution of the samples.
TOC Application Handbook
This handbook describes includes 50 TOC (Total Organic Carbon) application notes covering environmental, pharmaceutical, chemical, agricultural applications.
Examining the Role of TOC Analyzers in the Pharmaceutical Laboratory
Total Organic Carbon (TOC) analyzers are utilized across a wide range of industries for such measures as process and water quality control, experimental research, and EPA compliance. This white paper from Shimadzu examines the role of TOC analyzers within the pharmaceutical industry, where they serve vital roles in the manufacturing process. From inspections of the water used in drug manufacture (ultrapure water) to evaluation of cleaning effectiveness (cleaning validation), TOC analyzers are essential instruments in the pharmaceutical laboratory to ensure compliance with applicable regulations.
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