Derivatization Reagents for Acylation by Sigma-Aldrich Supelco

Supelco provides high quality derivatization reagents for acylation.Acylation, an alternative to silylation, allows the conversion of compounds with active hydrogen such as -OH, -SH, and -NH into esters, thioesters and amines, respectively. A very popular example of this method is the insertion of perfluoracyl groups to enable electron capture detection (ECD). Carbonyl groups adjacent to halogenated carbons enhance the ECD response.A further benefit of acylation is the formation of fragmentation... Read more


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Derivatization Reagents for Acylation

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Supelco provides high quality derivatization reagents for acylation.

Acylation, an alternative to silylation, allows the conversion of compounds with active hydrogen such as -OH, -SH, and -NH into esters, thioesters and amines, respectively. A very popular example of this method is the insertion of perfluoracyl groups to enable electron capture detection (ECD). Carbonyl groups adjacent to halogenated carbons enhance the ECD response.

A further benefit of acylation is the formation of fragmentation-directing derivatives for GC/MS analysis. Acylation reagents can be classified into two main groups: fluoro acid anhydrides and fluoracylimidazoles.

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Derivatization Reagents for Acylation by Sigma-Aldrich Supelco product image

Derivatization Reagents for Acylation

Manufacturer Sigma-Aldrich Supelco

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