Thermo Scientific™ FAIMS Pro Duo interface
Break free of sample complexity with enhanced selectivity and ultimate flexibility
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
Required a few optimisation but highly recommended!
Proteomics
The FAIMS application significantly increses the chance of identifying the wide-range of peptides.
Review Date: 18 Oct 2021 | Thermo Fisher Scientific
The Thermo Scientific™ FAIMS Pro Duo interface extends differential ion mobility to address analytical challenges for a broad range of qualitative and quantitative applications. Increase signal-to-noise ratios, sample throughput, and coverage for large- and small-molecule LC-MSn methods. Enhanced method optimization lets you easily integrate FAIMS selectivity into existing workflows.
Analysis of testosterone from human serum using FAIMS technology
LC/MS assays developed for the analysis of testosterone often exhibit high background signal that is difficult to eliminate by LC separation alone. This limits signal-to-noise ratio and ultimately limit of quantification of the assay. The FAIMS Pro Duo interface spatially separates ions based on alternating high and low electric fields applied to a set of cylindrical electrodes, enabling attenuation of matrix signal and increasing signal-to-noise.
This technical note from Thermo Fisher Scientific demonstrates improved limit of quantification for testosterone in human serum, utilizing the FAIMS Pro Duo interface on the TSQ Altis Plus mass spectrometer. Use of the FAIMS Pro Duo interface increased sensitivity 2-fold from 1 pg/mL to 0.5 pg/mL.
