SpectraMax® Paradigm Multi-Mode Microplate Detection Platform
High-throughput screening capability on one fast, configurable microplate reader
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Easy compliant use of plate reader
Plate-based assay
Equipment provides a user-friendly interphase with a 21CFR (Part 11) interphase that allows analysts to perform GxP assays. Templates and data are in-built and can be customizable for any assay and data is reported in the final format in few minutes. Easy to use and can be accessed from any where. No calculations or modification of raw data is required by the user.
Review Date: 9 Jan 2025 | Molecular Devices®
Many options in one instrument!
fluorescence, luminescence and absorption
The instrument offers various functions and can be used for many different methods. For an imaging core unit many functions can be combined in one instrument.. The software is easy to control and new projects are defined quickly. The machine can define the optimal excitation and emission for your fluorescent molecules. You can easily upgrade the instrument for cell analysis and counting and with the spectra drop, you can precisely quantify concentration of nucleic acid solutions in small volume.
Review Date: 4 Dec 2023 | Molecular Devices®
Best GMP-compliant equipment for Potency Assay
ELISA, Dose-response curve, FRET
This equipment has been built keeping industry folks like us in mind. It is easy to use, perfect for GMP use with 21 CFR features in-built. Easy to access from anywhere which gives wide range of flexibility for users to read, analyze and save files. The software is user-friendly any level of expertise and easy to manipulate which gives ample opportunities to create custom-built templates. Also, the technical sales force of this company is very helpful and always available for prompt service on-site whenever needed. Highly recommend them for every labs doing Bioassay, Cell/Gene Therapy!
Review Date: 5 Jun 2023 | Molecular Devices®
The SpectraMax® Paradigm® Multi-Mode Microplate Detection Platform is the only user upgradeable microplate reader on the market that allows for real-time system configuration by the user in less than two minutes. This revolution in modularity allows you to read what you want, when you want without compromising your biology. Although your detection needs may change, your equipment can stay the same simply by adding a new detection cartridge.
The Paradigm platform is supplied with SoftMax® Pro Microplate Data Acquistion & Analysis Software, Molecular Devices' industry leading all-in-one data acquisition and analysis software. Among the various ready-to-read protocols, users will find pre-written µ Max protocols enabling Low Volume applications measurement. Additionally, the Paradigm platform can be seamlessly integrated with the StakMax® Microplate Handling Stacker through the SoftMax Pro Software.
IMAP Phosphodiesterase Assays on SpectraMax Multi-Mode Microplate Readers
IMAP® Technology from Molecular Devices enables rapid, homogeneous, and non-radioactive assay of kinases, phosphatases, and phosphodiesterases and is suited for both assay development and high-throughput screening. IMAP assays are based on binding of phosphate to immobilized metal coordination complexes on nanoparticles.
Maximizing Performance of the SpectraDrop Micro-Volume Microplate for DNA Quantitation
Molecular Devices SpectraDrop™ Micro-Volume Microplate allows users to read up to 64 samples per plate on SpectraMax® Microplate Readers, with sample volumes as low as 2 µL. The SpectraDrop Microplate incorporates a specially designed adapter and a slide pair whose optical clarity allows measurements in absorbance and fluorescence modes to meet users’ application needs. The SpectraDrop Microplate’s slide design eliminates the need for calibration and gives consistent well-to-well reads with CVs below 5%.
Fluorescence-Based Quantitation of Small DNA Samples with the SpectraDrop Micro-Volume Microplate
Measurement of DNA using UV absorbance is a common method allowing quantitation of many sample types. However, some applications require quantitation of very low sample volumes or concentrations due to preparation method or scarcity of source material. For these applications, fluorescent DNA quantitation methods offer greater sensitivity and the ability to use smaller sample volumes with lower concentrations.
HTRF cAMP HiRange Assay on SpectraMax Multi-Mode Microplate Readers
In this application note we show how the SpectraMax® i3, SpectraMax® Paradigm®, and SpectraMax® M5e Multi-Mode Microplate Readers are used to perform robust, high-throughput HTRF® assays with excellent Z’ factors and highly reproducible EC50 values.
AlphaLISA Screen on the SpectraMax Paradigm Multi-Mode Microplate Detection Platform
Inflammation, the body’s reaction to infection, irritation, or other injury, is accompanied by increased endothelial chemokine production and adhesion molecule expression, which may result in an extensive neutrophil infiltration. The search for novel anti-inflammatory substances able to down-regulate these parameters, as well as tissue damage, holds great therapeutic promise. Screening for these new therapeutics requires a fast and sensitive platform for cytokine quantification.
