SpectraMax L Luminescence Microplate Reader
High sensitivity and high-throughput glow and flash luminescence detection in an upgradeable platform
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Pave the pathway to your future with the SpectraMax® L Microplate Luminometer. Measure flash and glow assays, including dual luciferase reporter gene, G protein-coupled receptor (GPCR) via aequorin, bioluminescence resonance energy transfer (BRET), and acridinium ester flash assays, in both 96- and 384-well plates. When you're ready to scale up, the SpectraMax L Reader can give you up to a six-fold increase in throughput with multi-channel configuration upgrade options. SoftMax Pro GxP Software and its software validation package give you comprehensive documentation and extensive data sets in CD-ROM format so you'll be able to meet FDA 21 CFR Part 11 and GxP compliance requirements.
Measuring Reactive Oxygen Species with SpectraMax Microplate Readers
Reactive Oxygen Species (ROS) are chemically reactive molecules containing oxygen. In eukaryotes, these molecules are mainly created during aerobic respiration and can cause problems, such as DNA damage and lipid peroxidation, resulting in cellular damage. ROS are also involved in apoptosis, cellular aging, and cell signaling. Naturally, cells protect themselves from these oxidative species with reducing enzymes and antioxidants, but as cells accumulate more ROS than can be processed, cells will shift towards a state of oxidative stress. Thus, the accurate measurement of cellular ROS levels is very important to understanding the roles ROS play in cellular biology and overall physiology.
