OrganoPlate® 3-lane
The OrganoPlate 3-lane features 40 independent culture cells, each supporting adjacent in-gel culture and 2 perfusion channels, that can contain perfused tubular tissues. The 3-lane models supports apical and basal access to epithelial and endothelial tubules, allowing barrier integrity and transport assays. The lanes are 400 micron wide. Six wells of the 384-well-plate user interface connect to each microfluidic network in…
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The OrganoPlate 3-lane features 40 independent culture cells, each supporting adjacent in-gel culture and 2 perfusion channels, that can contain perfused tubular tissues. The 3-lane models supports apical and basal access to epithelial and endothelial tubules, allowing barrier integrity and transport assays.
The lanes are 400 micron wide. Six wells of the 384-well-plate user interface connect to each microfluidic network in a 9x9 well grid, the central well provides viewing access to the microtissue.
Water immersion objectives for automated high-content imaging
Download this poster by Molecular Devices to find out if water immersion objectives, used to improve image quality in complex biological assays, could be used in a high-throughput environment.
High-Content Assay for Morphological Characterization of 3D Neuronal Networks in A Microfluidic Platform
The focus of this application note is to develop a high-throughput 3D neurite outgrowth assay using iPSC-derived neurons developed in the microfluidic OrganoPlate® platform, with the goal of establishing 3D models for neurodegenerative diseases and neurotoxicology screens. The OrganoPlate® is a high-throughput platform that combines the most recent advances in 3D cell culture, Phaseguides™ and microfluidics. The OrganoPlate contains 96 tissue chips suitable for long-term culture of live cells, is amenable for screening purposes, and is compatible with standard laboratory equipment or automated systems, such as the ImageXpress® Micro Confocal High-Content Imaging System.
Vascularization of 3D Tissues *In Vitro* with the OrganoPlate Graft
MIMETAS co-founder and CEO, Dr. Jos Joore, introduces the OrganoPlate® organ-on-a-chip device, a microfluidic 3D cell culture plate for complex disease modeling. Adding to the MIMETAS portfolio, in this video Joore also announces the OrganoPlate® Graft, the first in vitro cell culture technique for vascularization of 3D tissues.
This interview was filmed as part of our coverage of AACR 2019 - see other video highlights here >>
New Technology Enhances Organ Barrier Function Modeling
In this video, Bas Trietsch, Chief Technology Officer at Mimetas, presents the new OrganoTEER impedance spectrometer. This compact multi-channel platform enables the constant monitoring of 3D cell cultures under continuous perfusion, to give insight into disease states and the effects of pharmacological intervention on cell barrier functions and transport processes across those barriers.
This interview was filmed as part of our coverage of SLAS2019 - see other video highlights here >>
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