New Technology Enhances Organ Barrier Function Modeling
26 Feb 2019
In this video, Bas Trietsch, Chief Technology Officer at Mimetas, presents the new OrganoTEER impedance spectrometer. This compact multi-channel platform enables the constant monitoring of 3D cell cultures under continuous perfusion, to give insight into disease states and the effects of pharmacological intervention on cell barrier functions and transport processes across those barriers.
This interview was filmed as part of our coverage of SLAS2019 - see other video highlights here >>
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OrganoPlate® 3-lane
MIMETAS B.V.The OrganoPlate 3-lane features 40 independent culture cells, each supporting adjacent in-gel culture and 2 perfusion channels, that can contain perfused tubular tissues. The 3-lane models supports apical and basal access to epithelial and endothelial tubules, allowing barrier integrity and transport assays. The lanes are 400 micron wide. Six wells of the 384-well-plate user interface connect to each microfluidic network in a 9x9 well grid, the central well provides viewing access to the microtissue.
