HILICpak VT-50 2D
Polymer-based columns for Hydrophilic Interaction Chromatography.

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Columns for HILIC separation of anionic substances. Designed specially for phosphorylated sugars and pesticides like glyphosate.
- Suitable for anionic substances analysis by hydrophilic interaction chromatography (HILIC)
- Depends on the eluent selected, the column adds ion exchange mode
- Polymer-based packing material provides excellent chemical stability and minimum deterioration over extended time period
- Suitable for LC/MS
- Suitable for phosphorylated sugars
- Functional group: Quaternary ammonium
Brochures
Shodex HPLC Column Selection Guide
The following guide gives support in selecting the right HPLC column in order to get the best and maximum separation out of HPLC measurements. The guide is separated into 5 criteria to help ensure the right column is selected for the separation.
Simultaneous LC/MS analysis of ultra-short through long chain PFAS compounds (C1-C10) using multi-modal chromatography
Perfluoroalkyl and polyfluoroalkyl compounds (PFAS) are a structurally diverse class of manmade chemicals utilized in a variety of manufacturing processes since the 1960s. Due to their hydrophobic and lipophobic moieties, these compounds have high mobility in water and soil allowing their proliferation throughout the environment; further, the high bond strength of the C-F bond renders many PFAS indestructible in common environmental conditions and in human bodies, leading to bioaccumulation. Due to their links with adverse health effects, recalcitrance, and widespread occurrence in the environment, attention is focused on the ability to detect PFAS at low concentrations. In this poster, utilizing the Shodex VT-50 2D, a sensitive and repeatable assay of PFAS including ultra-short chain (C1-C4) though long chain (C8-C10) compounds was developed to explore the retention mechanism and MS sensitivity. The chromatographic separation utilized a polyvinyl alcohol solid support with quaternary ammonium surface functional groups, the VT-50 series, capable of multi-modal retention capabilities in buffered acetonitrile eluents.
HILIC Columns for Phosphorylated Sugar Analysis
Phosphorylated saccharides occupy a central position in carbohydrate metabolism. Numerous sugar interconversions occur when the sugars are linked to phosphates and di-phosphates. This application note describes the use of HILIC columns for phosphorylated sugar analysis.















