Gri3D® Hydrogel Microcavity Plates
Gri3D® Plates are designed to revolutionize 3D cell culture by offering unparalleled precision, scalability, and reproducibility. Each plate features a high-density array of hydrogel microcavities engineered to promote the uniform formation of organoids, enabling researchers to generate physiologically relevant 3D models with ease.
Place your order directly with the manufacturer.
Beautifully homogenous organoid cultures!
Drug screening on organoids
The plate is perfectly suited for high-throughput screening on organoids in 3D in a miniaturized fashion and with high replicate numbers. It allows great reproducibility and it can be easily adapted to different cellular models. The plate allows great quality imaging, including in high resolution. The protocols are clear and the system is very easy to use.
Review Date: 21 Dec 2023 | InSphero
Reproducible organoid cultures, easy to use
Lung organoids
The plates work really well to grow organoids in a reproducible manner. The media exchange port makes medium change a lot easier without disturbing the organoids. The imaging plates allow to take very good quality images. On top, the SUN team supports any technical questions along the way - they are amazing! Can only recommend.
Review Date: 30 Oct 2023 | InSphero
Amazing product support and results!
imaging intestinal organoids
The protocols are very clear and easy to follow. I highly recommend the plates especially for organoid imaging!
Review Date: 23 Oct 2023 | InSphero
Easy and reproducible platform to generate organoids
Characterization of organoid models and assays (drugs screening)
Platform to easily generate 3D cell cultures, as well as to maintain them (easy and fast media change). Moreover, this plate is compatible with many conventional assays and allows their effortless implementation as well as high reproducibility.
Review Date: 23 Oct 2023 | InSphero
Easy-to-use platform with high throughput
Molecule/drug screening
The plate is easy-to-use and offers high throughput data for 3D models as organoids and spheroids. The design is versatile which allowed us to select the best option for our models. The design is nice and help to maintain culture without disturbing them during medium changes for example. Maria who is in charge of the sells is really helpful and supportive. I recommend!
Review Date: 20 Oct 2023 | InSphero
Easy to use!
BBB spheroids
Easy to use plates, great attention to the customer problems/questions after the sale.
Review Date: 20 Oct 2023 | InSphero
Key Features:
- 96-well plates with in-well cavities ranging from 31 to 121 microcavities per well
- The dedicated pipetting port enables both manual and automated liquid handling with no loss of tissue.
- U-shaped microcavities made of PEG hydrogel ensure consistent, uniform organoid formation for reliable 3D culture results.
- Optically clear hydrogel microcavities eliminate light refraction, enabling high-quality confocal imaging without distortion.
- Non-adhesive PEG hydrogels naturally promote precise, size-controlled cell aggregation, from a few dozen to several thousand cells.
- SBS-standard Gri3D® plates are fully compatible with automated liquid handling systems, ensuring seamless integration into high-throughput workflows.
Gri3D® Plates are available in Polystyrene with a 1 mm bottom or with a 180 µm COP imaging membrane for superior optical clarity.
The Gri3D® Plates are available with the following microcavities diameters:
- 400 µm = 121 microcavities
- 500 µm =73 microcavities
- 600 µm =55 microcavities
- 800 µm =31 microcavities
The package includes one Gri3D® Hydrogel Microcavity Plate with lid, sterile.
Brochures
Explore the Gri3D microwell plates
In this product brochure from SUN Bioscience, explore the Gri3D®, the ready-to-use microwell plate designed for high-throughput, reproducible organoid culture. Based on a standard 96-microtiter plate, each well contains an ultra-dense U-bottom microwell array patterned in a cell-repellent hydrogel. Organoids are robustly generated in microwells, where they grow in suspension-like conditions and are located in the same imaging plane. A pipetting port on the side allows safe media exchange without microtissue loss.
High-throughput modeling of IBD using human intestinal organoids
Inflammatory bowel diseases (IBD) involve chronic inflammation of the gastrointestinal tract, which is often challenging to model accurately using traditional mouse models. Recent advancements in organoid technology provide a promising alternative for disease modeling and drug screening. In this application note, Molecular Devices presents Gri3D®, a high-throughput and reproducible 3D culture platform, which addresses the limitations of traditional methods by allowing the growth of human rectal organoids from single cells with high scalability and reproducibility.
This application note was written in association with SUN bioscience.
Microwell plates to standardize automated organoid workflows
Gri3D® is an all-in-one microwell plate allowing researchers in drug development and academia to establish and automate front-to-end 3D cell culture workflows.
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