Gri3D Hydrogel Microcavity Plates product manual

1 Jul 2026

This product manual provides detailed guidance on the use of Gri3D® Hydrogel Microcavity Plates for high-throughput organoid and spheroid culture. The platform uses PEG-based hydrogel microcavities to generate uniform 3D cell models within a standard 96-well format, supporting reproducible experimental conditions.

The manual outlines workflows for plate preparation, cell seeding, maintenance, and downstream applications. Organoids form within confined microcavities in a single focal plane, enabling efficient imaging and quantitative analysis. The system also supports automated handling and safe medium exchange via a dedicated pipetting port.

Resource details:

  • Resource type: Product brochure
  • Page count: 18
  • Read time: 28 mins

Gri3D® Hydrogel Microcavity Plates

InSphero

Gri3D® Plates are designed to revolutionize 3D cell culture by offering unparalleled precision, scalability, and reproducibility. Each plate features a high-density array of hydrogel microcavities engineered to promote the uniform formation of organoids, enabling researchers to generate physiologically relevant 3D models with ease.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.3D Cell CultureCulturing cells in three dimensions allows more physiologically relevant observations to be made regarding cellular interactions and gene expression. 3D models provide a more accurate representation of cells in vivo and are more stable than 2D cultures, making them very useful for long-term studies.OrganoidsHigh Throughput Screening