ADME-Toxicology Products & Reviews

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ADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Seahorse XF HS Mini Analyzer

Agilent Technologies

Agilent Seahorse XF HS Mini Analyzers measure mitochondrial respiration and glycolysis as well as ATP production rate of live cells in an eight-well miniplate format. The quick and easy setup makes the Seahorse XF HS Mini Analyzer ideal for performing routine energy metabolism measurements of ex-vivo and other quantity-limited samples.

4.7/5.0
|1 Review
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Seahorse XF Pro Analyzer

Agilent Technologies

Measure mitochondrial respiration, glycolysis, and ATP production rates in live cells in a 96-well forma t, providing a system-level view of cellular energy metabolism and mitochondrial health. It combines enhanced sensitivity and data consistency with intuitive software and advanced data analytics, enabling users to streamline assay workflow from start to finish and generate and interpret metabolic data easily. 

4.7/5.0
|8 Reviews
  • Best New Drug Discovery & Development Product of the Year
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HoloMonitor M4FL Live Cell Analysis System

Phase Holographic Imaging (PHI)

The HoloMonitor ® live cell imaging system enables long-term non-invasive analysis of cell cultures within your standard incubator. With the latest add-on fluorescence module, cell biologists benefit from minimizing light exposure and reducing photocytotoxicity when automatically obtaining accurate live-cell morphology, migration, proliferation data, and multi-well time-lapse videos down to a single-cell level in real-time.

4.7/5.0
|1 Review
  • Best New Analytical Science Product of the Year
  • Best New Life Sciences Product of the Year
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EVE Plus - One of the Fastest Cell Counters

NanoEntek

EVE™ Plus, one of the world’s fastest automated cell counters, is designed to measure cell count and viability with accuracy and precision by using the standard trypan blue technique within 1 second. EVE™ Plus also identifies and counts clumpy cells as several individual cells for accurate analysis.

4.8/5.0
|53 Reviews
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ApoTox-Glo™ Triplex Assay

Promega Corp.

The ApoTox-Glo™ Triplex Assay combines three assay chemistries to easily assess viability, cytotoxicity and apoptosis events in the same cell-based assay well. First, viability and cytotoxicity are determined by measuring two differential protease biomarkers simultaneously with the addition of a single nonlytic reagent containing two peptide substrates. The live-cell protease activity is restricted to intact viable cells and i…

4.6/5.0
|3 Reviews

Glucose-6-Phosphate Dehydrogenase Activity Assay Kit

BioVision Inc

Kit Summary: • Detection method- Absorbance (450 nm) • Sample type- Cell and Tissue culture supernatants, urine, plasma and serum, as well as many other biological fluids etc. • Species reactivity- Mammalian • Application- The G6PDH Assay Kit can detect as low as 0.04mU G6PDH per well. Features & Benefits: • Simple procedure; takes ~ 30-60 minutes • Fast and convenient Kit components: • G6PDH Assay Buffer • G6PDH Substrate • G…

4.5/5.0
|2 Reviews


Griess Reagent System

Promega Corp.

The Griess Reagent System measures nitrite (NO2–), which is one of two primary stable and nonvolatile breakdown products of nitric oxide (NO). Nitric oxide is an important physiological messenger and effector molecule in many biological systems, including immunological, neuronal and cardiovascular tissues. This assay relies on a diazotization reaction that was originally described by Griess in 1879. Through the years, many mod…

4.7/5.0
|1 Review

Annexin V : FITC Apoptosis Detection Kit I

BD Biosciences

Apoptosis is a normal physiologic process which occurs during embryonic development as well as in maintenence of tissue homeostasis. The apoptotic program is characterized by certain morphologic features, including loss of plasma membrane asymmetry and attachment, condensation of the cytoplasm and nucleus, and internucleosomal cleavage of DNA. Loss of plasma membrane is one of the earliest features. In apoptotic cells, the mem…

4.5/5.0
|2 Reviews

ROS-Glo™ H2O2 Assay

Promega Corp.

The ROS-Glo™ H2O2 Assay is a homogeneous, fast and sensitive bioluminescent assay that measures the level of hydrogen peroxide (H2O2), a reactive oxygen species (ROS), directly in cell culture or in defined enzyme reactions.   This assay allows identification of conditions or test compounds, such as small molecule inhibitors or inducers, that alter ROS levels. The scalable multiwell format couples a stable luminescent si…

5.0/5.0
|2 Reviews




Vivid® CYP2D6 Cyan Screening Kit

Thermo Fisher Scientific

Vivid® CYP450 Screening Kits are high-throughput fluorescence-based assays for detection of enzyme-drug interactions and CYP450 inhibition. They provide an optimized method for studying isozyme-specific CYP450-drug interactions, metabolism, and inhibition. Vivid® CYP450 Screening Kits offer: Easy three-step procedure, "mix and read" format, reactions at room temperature or 37°C. Superior fluorescent properties and k…

4.7/5.0
|1 Review