UHPLC and HPLC Columns Products & Reviews

Hypersil APS-2 columns can be used with traditional buffers and organic additives as a weak anion exchanger for the analysis of anions and organic acids. Product detail: Hypersil APS-2 columns are a versatile aminopropyl group stationary phase which can be used in 3 modes: ion chromatography (weak anion exchanger), reversed phase and normal phase chromatography. Hypersil APS-2 columns can be used with traditional buffers a…

ACQUITY UPLC® BEH HILIC columns contain the rugged 1.7 μm unbonded BEH particles and are designed to retain and separate very polar basic compounds.These unique columns are optimized and tested to produce efficient and reproducible separations under UPLC® HILIC conditions. ACQUITY UPLC BEH HILIC columns overcome a major weakness of HILIC stationary phases: chemical stability. The unbonded silica stationary phases often used in…

Exceptional Resolution of Oligonucleotide Mixtures

This new strong anion exchange resin offers an optimised macro-porous structure that ensures an efficient purification of large biomolecules, such as adeno-associated viruses (AAVs) and plasmid DNA (pDNA). With its high binding capacity for such molecules and high separation efficiency even at elevated flow rates, MacroSep IEX Q is a perfect addition to DSP platforms.

YMC-Actus prepacked (semi-)preparative HPLC columns show high stability and long lifetimes even under high flow rates and steep gradient conditions without any void volume formation.

BioPro IEX, YMC's strong ion exchange material are based on a hydrophilic polymer which provides low non-specific adsorption and high recoveries. Porous and non-porous polymer beads are available for high loadability and throughput.  

YMC provides silica-based SEC phases with a dihydroxypropyl modification in 4 different pore sizes.

YMC-SEC MAB is a silica-based size exclusion chromatography column utilizing a dihydroxypropyl stationary phase bonded to a silica gel base, specifically designed for antibody separations.

BioPro HIC columns based on non-porous hydrophilic polymer beads and functionalised with butyl chains are optimised for the analysis of antibodies, antibody-drug conjugates (ADCs) and other proteins.

With YMC-Triart Prep, pH stable preparative HPLC stationary phases are available for industrial-scale applications. This hybrid silica-based material can be used in a pH range of 2.0 - 10.0 and allows more efficient cleaning procedures. The innovative YMC-Triart Prep combines mechanical strength and pH stability.

BioPro IEX and BioPro IEX SmartSep resins are specifically designed for biochromatography. They are available as a strong anion exchanger (BioPro IEX Q) and a strong cation exchanger (BioPro IEX S). The resins are based on a hydrophilic polymer matrix, with a particle size of 10 µm, 20 µm, 30 µm and 75 µm.

1 mm UHPLC columns are available in different lengths packed with the highly robust 1.9 µm YMC-Triart C18 particles.  

Highly robust hybrid silica material for the purification of proteins, peptides and oligonucleotides, which combines mechanical strength and pH stability. The larger pore size makes YMC Triart-Prep Bio200 C8 the ideal choice for the purification of mid-size to large biomolecules.

SEC Analytical Column optimized for MALS. Standard-bore for standard proteins in aqueous solvents.

The Antibody column package includes modern protein A affinity and size exclusion chromatography columns to obtain highly pure human IgG.

Optimized for peptides and small proteins by SEC-MALS.

Optimized for AAVs, large proteins, and RNAs/DNAs by SEC-MALS.

Optimized for proteins by SEC-MALS. Narrow-bore for ultimate detection sensitivity when used with a low dispersion (U)HPLC system.

GTxResolve Premier columns batch tested for recovery and resolution of nucleic acids and protein containing samples. With surface technologies and methods optimized for mRNA, LNP and viral vector applications.

Optimized for proteins by SEC-MALS.

SEC Analytical Column optimized for MALS. Narrow-bore for membrane proteins in aqueous solvents.

SEC Analytical Column optimized for MALS. Standard-bore for membrane proteins in aqueous solvents.

GTxResolve Premier columns batch tested for recovery and resolution of nucleic acids and protein containing samples. With Surface technologies and methods optimized for mRNA, LNP and viral vector applications.

Superdex™ 75 Increase 10/300 GL, 5/150 GL, and 3.2/300 are prepacked columns for versatile use in size exclusion chromatography applications. The columns are intended for use in preparative purification as well as for characterization and analysis of proteins with molecular weights between Mr 3000 and 70 000, such as recombinant tagged proteins.

Optimized for AAVs, large proteins, and RNAs/DNAs by SEC-MALS. Narrow-bore for ultimate detection sensitivity when used with a low dispersion (U)HPLC system.