Drug discovery > Lead Discovery Products & Reviews

Protein/Peptide Columns

LC/GC Certified vials are tested by LC/UV for residues of chemicals used in processing and packaging vials. The septa are tested by headspace GC to ensure low levels of low molecular weight polymer. These vials are suited for analyte concentration in the µg/mL concentration; typically detectors like UV and RI.

Most chromatographers have experienced problems retaining and separating polar compounds using conventional reversed-phase chromatography.  These difficult-to-analyze compounds either pass through the column unretained or, if retained at all, co-elute at the beginning of the chromatogram.  Waters AtlantisTM columns are designed for these types of challenging separations and are available in two chemistries: dC18 and HILIC sili…

Vantage-L Laboratory Columns provide advanced design for the increased demands of biochromatography. Five diameters and three lengths provide a range of column volumes and bed heights to select from, with the twin adjusters providing 250 mm adjustment in all columns. A 7 bar pressure rating and resistance to commonly used solvents makes them ideally suited to the newer smaller particle media applications.Minimal components and…

Universal, HTS Kinase Screening Assays Use higher ATP concentrations: Linear response up to 500μM ATP. Use any kinase and kinase-substrate combination, including peptide, protein, lipid, and sugar substrates. Perform the assay without substrate modifications. Obtain reliable results: Z´-factor values routinely >0.7. Reduce false hits: Luminescence is much less susceptible to interference from library compounds t…

Roche NimbleGen provides the most sensitive and specific DNA Methylation microarrays and services on the market. Methylated DNA regions are accurately mapped using a combination of affinity-based enrichment, such as Methylated DNA Immunoprecipitation (MeDIP) or the Methylated CpG Island Recovery Assay (MIRA), followed by microarray analysis. Roche NimbleGen offers several types of DNA Methylation arrays for a variety of organi…

CE Instruments provides service support and training for Carlo Erba, Fisons and Thermo GCs and a wide range of specialist GC accessories and Gas analysis systems.

Higher Efficiencies.  Faster Analysis.  Reduced Back Pressures.

The world’s only laser-based microplate nephelometer

Corning® 500 mL Bottle Top Vacuum Filter, 0.22 µm Pore 33.2cm2 PES Membrane, Fits 45mm Diameter Necks, Sterile, 12/CaseFits plastic or glass media bottles with 45mm neck sizes.Polyethersulfone (PES) membranes provide the fastest flow rates, the lowest protein binding and low extractables and are best for filtering cell culture media.Angled hose connector simplifies vacuum line attachment.Individually packaged, sterile and cert…

Available prelabelled with bar-code sequentially numbered with unique numbers using code 39, 7 digits

The Waters Regulated Bioanalysis Platform Solution with UNIFI®is a single-vendor solution for bioanalytical laboratories to generate quantitative results while maintaining optimal productivity, quality and consistency to maximize up-time and cost per sample.The UNIFI Scientific Information System is designed to accelerate your capabilities and anticipate your imperatives. The platform enhances your ability to develop robust m…

Whether you are performing high throughput compound confirmation, identifying natural products or metabolites, or analyzing peptides and proteins, Waters® Exact Mass LC/MS Systems that incorporate the LCT PremierÔ Mass Spectrometer provide a total solution that maximizes performance for your application. The fully integrated systems are controlled from a single data system, maximizing the efficiency of your analysis while enab…

Maximum Yields of High Quality DNA. Optimized for maximum binding yield of DNA from a variety of sample types New well geometry results in reduced hold-up volume and higher recovery of DNA New outlet tip geometry provides direct flow of samples into receiver plate without concerns of crosscontamination Enhanced membrane ensures high yields of contaminant-free DNA for downstream applications Manufactured in accordance with SBS…

This comprehensive range of high quality Lamps represents excellent value, helping to cut your replacement costs. Every lamp is covered by a full 30 day warranty.

The Thermo Scientific KingFisher Duo magnetic particle processor and KingFisher optimized reagent kits provide everything you need to get high yields of quality nucleic acid for downstream applications. The compact KingFisher Duo instrument is ideal for space-restricted laboratories that are looking to reduce hands-on time required for purifying DNA/RNA, cells or proteins. It can be used with a variety of starting materials,…

The Thermo Scientific KingFisher Flex magnetic particle processor offers great flexibility for high-throughput purification of DNA/RNA, proteins and cells from virtually any source.Using patented magnetic particle separation technology, the KingFisher Flex provides a fast and easy way to get high yields of purified samples with excellent reproducibility and quality.Key Features: High-throughput system processes up to 96 sa…

Chromolith® HighResolution: High resolution separations without ultra high pressure. The revolutionary monolithic Chromolith® HighResolution columns are made from a single rod of high-purity monolithic silica, rather than from particles. Their unique bimodal pore structure allows the chromatographic performance to be improved significantly. Speed of analysis (separations up to 9 times faster if required) Separations two…

CALLI provides target dosage of powders and liquid handling in combination with precise weighing, thereby supplying the ideal tools for sample preparation. All media, liquid or dry powders, can be distributed and diluted by weight and if necessary, dissolved with vortexing or sonication. All steps are automatically executed with maximum reliability and reproducibility. For precise weighing the most modern Sartorius Genius bala…

Round well design with a clear flat bottom 2.8mm distance between well bottoms to plate bottom 50 µL total well volume, with recommended working volume of 5-40 µL High base plate design is compatible with automation and for bar coding Validated by Molecular Devices for the FLIPR reader. Outer wells aligned for proper viewing with FLIPR Surface treated for enhanced cell attachment Ideal for miniaturized 384 well fluores…

Clarity Chromatography Software Clarity is advanced chromatography data station with software modules for data acquisition, data processing and instrument control. Its wide range of data acquisition interfaces ( A/D converters, LAN, USB, RS232) allows conection to virtually any chromatograph.  The standard set of features can be extended by optional software modules such as GPC, PDA, EA, CE and SST. Clarity Chromatography Sof…

Known world-wide as a leading manufacturer of high purity inorganic compounds, Alfa Aesar produces thousands of separate inorganics used in a variety of research and production applications. These products include base metal compounds, rare earth compounds and ultra dry materials for air and moisture sensitive applications. These and many more products are available from our main catalogue and through our on-line, real-time ca…

The Explorer SpeedVac System is a computer controlled, bench-top centrifugal concentrator perfect for drug discovery applications. It is designed to provide repeatable, accurate results and monitor sample temperature to protect samples from over heating. The six-position rotor and comprehensive range of sample carriers gives you flexibility in your sample format. Product Detail The Explorer SpeedVac System is a fully modu…

The integrated, SPD bench-top SpeedVac concentrator is ideal for aqueous and non-aggressive solvent evaporation as well as DNA applications.It has an oil-free vacuum pump and refrigerated vapor trap incorporated making it a fully integrated system.Product Detail The SPD integrated SpeedVac has a vacuum pump, cold-trap and concentrator fully integrated into one convenient system.  Digital programming enhances the simplicity of…