Clonal Genes
Twist Bioscience’s platform is capable of synthesizing thousands of genes each day to meet all your DNA needs. Our silicon-based scalability and high precision oligo production results in high quality DNA synthesis and assembly; qualities that allow Twist to create perfect genes of various lengths and difficulty, NGS-verified and delivered on-time when you need them.
Place your order directly with the manufacturer.
Twist is better than me at cloning synthetic genes
Protein engineering
I have become a big fan of Twist Clonal Genes after years of buying synthetic gene fragments from other companies and cloning them myself. Twist does the cloning and sequencing much faster than I ever did. I invest the time that Twist saves me into projects that cannot be outsourced, at least not yet. The process of onboarding custom vectors, which saves me the effort of subcloning, was easier and cheaper than I expected, and brought to my attention a discrepancy between a sequence that I was given and the actual sequence of a plasmid that I had been using for years. My only regret is that I didn't start using this service much earlier, but for that I have only myself to blame.
Review Date: 10 Sept 2026 | Twist Bioscience
Reliable gene synthesis with responsive support
Gene synthesis for de novo designed proteins
We have been using Twist for many years to synthesize our genes. What we appreciate most is the quality of the constructs and the customer service, which is usually very responsive. The ordering platform is easy to use, and their shipping and tracking are reliable.
Review Date: 30 Aug 2026 | Twist Bioscience
Perfect on ordering, and project starting fast, delivery fast
Gene synthesis
Good service, fast response on ordering, and quick shipment.
Review Date: 28 Aug 2026 | Twist Bioscience
Great value and time savings
Mitochondrial Biology
Having these constructs synthesized with 100% accuracy greatly increases the speed and throughput of what I can do as an individual scientist. I have accumulated a large library of parts to rapidly design test and optimize hundreds of constructs that would have taken months to generate from scratch. This lets me get to doing actual science that tests my hypothesis instead of molecular biology troubleshooting.
Review Date: 18 Aug 2026 | Twist Bioscience
Does the job
Plants molecular biology
Great, everything is ok, but shipping and fees are a little expensive.
Review Date: 10 Aug 2026 | Twist Bioscience
Reliable, Fast, Inexpensive
Biologics Production
My company is a repeat customer with Twist. They are reliable, cost effective and great to deal with. We routinely send complex genes to Twist and they just get the job done. Looking forward to sending future orders.
Review Date: 6 Aug 2026 | Twist Bioscience
Twist Bioscience: Fast, Reliable, High‑Quality Gene Synthesis Partner
Biomedicine, Immunotherapy
Twist Bioscience has been an excellent partner for gene synthesis. Their turnaround times are fast, the ordering process is straightforward, and the sequence quality has been consistently strong across multiple projects. I especially appreciate the reliability and the clear communication throughout the process, which makes planning experiments much easier. The ability to get accurate synthetic genes delivered on schedule has saved time and helped keep our research moving efficiently. Overall, Twist Bioscience has been a very dependable choice for gene synthesis.
Review Date: 31 Jul 2026 | Twist Bioscience
We can highly recommend the gene synthesis service at Twist Bioscience
Basic science, applied science
Twist Bioscience has now synthesized three genes for us. All sequences were perfect and the genes were functional and extremely useful to solve our scientific questions. Gene synthesis is very fast and we were always updated about the current stage of the project.
Review Date: 24 Jul 2026 | Twist Bioscience
Outstanding product and support for our iGEM student team
CasSTAR: CRISPR-Cas12a diagnostics for antibiotic resistance (iGEM 2026)
We are an iGEM 2026 student team (iGEM Hamburg, TUHH and Universität Hamburg), and we received our Twist Clonal Genes through Twist's iGEM sponsorship rather than as a paid order. From start to finish the experience was excellent. Before ordering, we reached out with a number of questions, and Rebecca and Eric were both responsive, patient, and genuinely helpful. For a student team taking on a fairly ambitious project, that level of support made a real difference and was an important early step in getting our pipeline moving. The documentation was clear and thorough. The product quality has been outstanding. This week we completed transformation and after miniprep measured over 290 ng/µL, an unusually strong result for us. Everything arrived as described and performed exactly as we hoped. If we have anything to say, it is simply a big thank you to Rebecca, Eric, and the whole Twist team for supporting student science. We would gladly work with Twist again.
Review Date: 9 Jul 2026 | Twist Bioscience
Great service
Neuroscience
I ordered 8 plasmids based on a common (custom) backbone - all arrived faster than expected, with perfect sequences and at a much lower price than competitors. The sales reps before I made my purchase were helpful and efficient but not overbearing. My only criticism would be that they could have more options for stock vectors (e.g. AAV vectors).
Review Date: 22 Jun 2026 | Twist Bioscience
Twist Bioscience is transforming gene synthesis, a process at the core of synthetic and molecular biology. Our silicon-based DNA writing platform significantly increases gene synthesis throughput and scalability, while also reducing turnaround time and price per base. Twist’s Clonal Genes offering gives you the flexibility to get the DNA you want, the way you want it. Choose the amount of DNA, and the format you want it in to drive your research. Because every clonal gene is NGS-verified, you can be sure you’re getting the perfect cloned gene every time.
SPECS:
- 0.3–5.0 kb cloned into a Twist Vectoror your vector of choice
- 100% accurate NGS-verified gene sequences
- DNA mass options:
- 50 ng–2 μg
- 2–10 μg
- 10–100 μg
- 100–1,000 μg
- Normalization
- Endotoxin free
- No order limit
From target to molecule: A comprehensive guide to antibody discovery and development
In this application eBook, discover a comprehensive guide to antibody discovery and development with considerations and approaches for the biopharma industry. Explore how new techniques have made this entire process more rapid, cost-effective, and targeted.
Multiple focused CRISPR libraries from a single oligo pool
Functional genetic screening using the CRISPR/Cas9 system is a powerful tool for interrogating gene function at scale, but access to and implementation of this technology is constrained by existing pre-defined CRISPR sgRNA libraries.
In this application note, a single Twist Oligo Pool was used in combination with Custom Library Multiplexed Cloning, an easy-to-use bioinformatics and wet-lab workflow, to generate numerous high-quality, custom sgRNA libraries.
Twist Bioscience synthetic DNA helps Berkeley Brewing Science produce unique yeast strains for better brews
In this application note, Berkeley Brewing Science outlines the development of unique yeast strains that aim to make brewing more sustainable and promise delicious new aromas and flavours for craft beers. To achieve this, Berkeley Brewing Science uses quality synthetic DNA from Twist Bioscience.
Pathway Engineering Through 5 kb Gene Synthesis
A rapid design-build-test cycle is vital to metabolic engineering applications in which researchers re-program microorganisms to produce non-native molecules of interest. To produce these molecules, researchers typically add one gene or an entire pathway of genes into a host organism. These genes encode proteins or enzymes that, when expressed in a microbial host, convert a common substrate into a molecule of interest. Using microbial synthesis as an alternative to chemical synthesis or extraction can yield the same compounds more quickly, at a lower cost, and with fewer environmental impacts.
Clonal Genes: Design. Build. Test.
Twist Bioscience is transforming gene synthesis, a process at the core of synthetic and molecular biology. Our silicon-based DNA writing platform significantly increases gene synthesis throughput and scalability, while also reducing turnaround time and price per base. Think on a new scale in your gene designs, and accelerate your discoveries.
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Twist Bioscience and Neogene partner for next-generation personalized T cell therapies
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The partnership aims to bring access to Twist's proprietary phage display libraries for the discovery of antibodies in Takeda's biologics pipeline
