Clonal Genes
Twist Bioscience’s platform is capable of synthesizing thousands of genes each day to meet all your DNA needs. Our silicon-based scalability and high precision oligo production results in high quality DNA synthesis and assembly; qualities that allow Twist to create perfect genes of various lengths and difficulty, NGS-verified and delivered on-time when you need them.
Place your order directly with the manufacturer.
Outstanding product and support for our iGEM student team
CasSTAR: CRISPR-Cas12a diagnostics for antibiotic resistance (iGEM 2026)
We are an iGEM 2026 student team (iGEM Hamburg, TUHH and Universität Hamburg), and we received our Twist Clonal Genes through Twist's iGEM sponsorship rather than as a paid order. From start to finish the experience was excellent. Before ordering, we reached out with a number of questions, and Rebecca and Eric were both responsive, patient, and genuinely helpful. For a student team taking on a fairly ambitious project, that level of support made a real difference and was an important early step in getting our pipeline moving. The documentation was clear and thorough. The product quality has been outstanding. This week we completed transformation and after miniprep measured over 290 ng/µL, an unusually strong result for us. Everything arrived as described and performed exactly as we hoped. If we have anything to say, it is simply a big thank you to Rebecca, Eric, and the whole Twist team for supporting student science. We would gladly work with Twist again.
Review Date: 9 Jul 2026 | Twist Bioscience
Great service
Neuroscience
I ordered 8 plasmids based on a common (custom) backbone - all arrived faster than expected, with perfect sequences and at a much lower price than competitors. The sales reps before I made my purchase were helpful and efficient but not overbearing. My only criticism would be that they could have more options for stock vectors (e.g. AAV vectors).
Review Date: 22 Jun 2026 | Twist Bioscience
Superb service despite technical challenges
Custom gene expression
I have been extremely impressed with Twist. A few of our constructs kept failing because of presumed toxicity to E.coli. Despite this, I was offered bespoke codon optimisation and custom growth conditions until eventually, everything worked. We have now received all constructs for this order, and we were kept up to date at every stage of the process. I will definitely be using Twist again and recommending them widely.
Review Date: 18 Jun 2026 | Twist Bioscience
Cost effective and fast turn around
Molecular Biology
I’ve worked with several gene synthesis providers and found Twist Bioscience to be the best overall. Their turnaround time and pricing are significantly better than those of other companies I’ve used. I would highly recommend Twist for both gene synthesis and clonal gene services.
Review Date: 27 May 2026 | Twist Bioscience
Top service
Neuroscience research
Excellent service for synthetic cDNA in expression vectors. Fast, reliable, and makes molecular biology easy from your office!
Review Date: 27 Apr 2026 | Twist Bioscience
Positive experience
Cloning expression vector
I used Twist Bioscience for gene synthesis and cloning into an expression vector, and I had a very positive experience. The ordering process was straightforward, with an intuitive design interface that made it easy to submit my construct. The turnaround time met expectations.
Review Date: 17 Apr 2026 | Twist Bioscience
Great ordering software!
Clonal Gene Synthesis
I really enjoy ordering from Twist Biosciences. The ordering software is simple and easy to use. Optimizing your constructs is simple and yields excellent results. I can easily import my genes and optimize them for my chosen vector. Retaining DNA sequences that are useful for cloning or expression is easy while also codon optimizing my gene of interest for my expression system.
Review Date: 13 Apr 2026 | Twist Bioscience
Support was helpful and so was the price
Recombinant Protein Production
Twist’s DNA cloning was reasonably priced and support was very helpful for issues, if any, in manufacturing! Ordering was easy through the online portal.
Review Date: 10 Apr 2026 | Twist Bioscience
gold standard for cloning
biological research
TwistBio helped a lot my research, making possible the effectiveness of my biological question. Not only this, they helped me throughout all the procedure of ordering, cloning and shipment, with a very reasonable price.
Review Date: 8 Apr 2026 | Twist Bioscience
Excellent service.
Gene expression plasmids
Easy ordering process, fast synthesis and delivery, and very good technical support when required. The clonal genes also represent competitive pricing too.
Review Date: 17 Mar 2026 | Twist Bioscience
Twist Bioscience is transforming gene synthesis, a process at the core of synthetic and molecular biology. Our silicon-based DNA writing platform significantly increases gene synthesis throughput and scalability, while also reducing turnaround time and price per base. Twist’s Clonal Genes offering gives you the flexibility to get the DNA you want, the way you want it. Choose the amount of DNA, and the format you want it in to drive your research. Because every clonal gene is NGS-verified, you can be sure you’re getting the perfect cloned gene every time.
SPECS:
- 0.3–5.0 kb cloned into a Twist Vectoror your vector of choice
- 100% accurate NGS-verified gene sequences
- DNA mass options:
- 50 ng–2 μg
- 2–10 μg
- 10–100 μg
- 100–1,000 μg
- Normalization
- Endotoxin free
- No order limit
From target to molecule: A comprehensive guide to antibody discovery and development
In this application eBook, discover a comprehensive guide to antibody discovery and development with considerations and approaches for the biopharma industry. Explore how new techniques have made this entire process more rapid, cost-effective, and targeted.
Multiple focused CRISPR libraries from a single oligo pool
Functional genetic screening using the CRISPR/Cas9 system is a powerful tool for interrogating gene function at scale, but access to and implementation of this technology is constrained by existing pre-defined CRISPR sgRNA libraries.
In this application note, a single Twist Oligo Pool was used in combination with Custom Library Multiplexed Cloning, an easy-to-use bioinformatics and wet-lab workflow, to generate numerous high-quality, custom sgRNA libraries.
Twist Bioscience synthetic DNA helps Berkeley Brewing Science produce unique yeast strains for better brews
In this application note, Berkeley Brewing Science outlines the development of unique yeast strains that aim to make brewing more sustainable and promise delicious new aromas and flavours for craft beers. To achieve this, Berkeley Brewing Science uses quality synthetic DNA from Twist Bioscience.
Pathway Engineering Through 5 kb Gene Synthesis
A rapid design-build-test cycle is vital to metabolic engineering applications in which researchers re-program microorganisms to produce non-native molecules of interest. To produce these molecules, researchers typically add one gene or an entire pathway of genes into a host organism. These genes encode proteins or enzymes that, when expressed in a microbial host, convert a common substrate into a molecule of interest. Using microbial synthesis as an alternative to chemical synthesis or extraction can yield the same compounds more quickly, at a lower cost, and with fewer environmental impacts.
Clonal Genes: Design. Build. Test.
Twist Bioscience is transforming gene synthesis, a process at the core of synthetic and molecular biology. Our silicon-based DNA writing platform significantly increases gene synthesis throughput and scalability, while also reducing turnaround time and price per base. Think on a new scale in your gene designs, and accelerate your discoveries.
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Twist Bioscience and Neogene partner for next-generation personalized T cell therapies
Partnership combines Twist’s leadership in DNA synthesis and synthetic biology with Neogene’s expertise in personalized engineered T cell therapies
Takeda partners with Twist Bioscience to expand biologics discovery capabilities
The partnership aims to bring access to Twist's proprietary phage display libraries for the discovery of antibodies in Takeda's biologics pipeline
