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Metabolite Identification (Met ID) for Oligonucleotides

ChemPartner

Our Metabolite Identification service employs HRMS /LC-MS/MS to decode degradation pathways of antisense oligonucleotides (ASOs), siRNAs, and modified variants, identifying chain-shortened metabolites (5’/3’ cleavage), phosphorothioate changes (desulfurization, inversion) and base/nucleotide alterations (deamination/depurination). Through plasma/tissue/cell analysis, we reveal metabolic stability, biodistribution, and exonucle…

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SPATIAL

ariadne.ai

An intuitive browser-based tool for spatial omics data analysis. Simple to use with datasets created by any microscope, SPATIAL features best-in-class image alignment, cell and tissue segmentation.

0.0/5.0
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Biotinylated Human VEGF165 Protein, His,Avitag™

ACROBiosystems

Biotinylated Human VEGF165, His,Avitag(VE5-H82Q0) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag™), and has a calculated MW of 22.4 kDa (monomer). The protein migrates as 25-33 kDa (monomer) under reducing (R) condition, and 42-55 kDa (homodimer) under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

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Metabolite Identification (Met ID) for ADC

ChemPartner

Our Metabolite Identification service for Antibody-Drug Conjugates (ADCs) applies immuno-capture and HRMS to detect payload-containing catabolites, linker cleavages, and biotransformations in biological samples. This targeted assay quantifies free payloads, metabolites, and intact conjugates, assessing stability and off-target risks. Essential for ADC development, it informs payload design and pharmacokinetics, ensuring compli…

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Biacore™ Insight Software

Cytiva

Unified software platform for easy and efficient instrument control and data evaluation of Biacore™ 1 series and Biacore 8 series SPR systems, with the option to integrate into GxP- regulated workflows.

0.0/5.0
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