Drug Discovery & Development Products & Reviews

Achieve precise measurement of challenging large and highly heterogeneous molecules that were previously out of reach for mass characterization.

Screen for high-producing, viable clones—faster and with greater confidence

Human Claudin-18.2 Full Length Protein-VLP (CL2-H52P7) is expressed from human 293 cells (HEK293). Virus-like particles(VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrane Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures.

Human VEGF165, His Tag (VE5-H5248) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the N-terminus, and has a calculated MW of 21.1 kDa. The protein migrates as 27-28 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Comprehensive Quantitation & Confident Structural ID

BioIVT is the leading provider of quality, highly characterized, ethically procured ADME research products, featuring custom preparation or extensive ready-to-ship inventory, large lot sizes and expert support.

Stable Isotope-labeled Products for Drug Screening and Analysis

ISOAPI-D™: Built Specifically for the Next Generation of Deuterated Reagents in Pharmaceutical Development

Simplify synthesis and scale-up of potent mRNA with third-generation CleanCap®—proven technology for enhanced in vivo translatability.

Isolated immune cells play a crucial role across the stages of drug discovery and development from biomarker and target identification through screening and safety assessment to manufacturing. They can be used to create disease models, cell lines, gene editing techniques and more.

Our Protein Binding Platform assesses drug-protein interactions using equilibrium dialysis and ultracentrifugation methods to determine unbound fractions and distribution in biological samples including plasma, blood, tissues, and cells. This essential ADME service evaluates reversible drug transfer between compartments, providing insights into pharmacokinetics, bioavailability, and potential interactions.

MAGic™ Beads Protein A offer one-step clarification and capture of monoclonal antibodies, eliminating the need for centrifugation, depth filtration and Protein A affinity column-chromatography. Super-paramagnetic porous beads coupled with an alkali resistant Protein A ligand.

Myelotracker® is a cutting-edge fluorescent probe that enables precise detection of neutrophils—essential immune cells—in both blood and tissue samples. It offers researchers a dependable tool for exploring inflammation, infections, and immune system activity.

A sensitive and robust assay to easily detect mouse IgG antibodies in picodroplets.

Pion’s PAMPA high-throughput permeability assay uses a range of membranes to mimic physiologic conditions. It allows you to evaluate the passive permeability of API’s as well as the absorption potential of simple or complex formulations using robust models and protocols in a 96-well format.

Speed-controlled vacuum source

pHSense probes for internalization studies

Our hERG Safety Screening service employs the Synchropatch-384 automated patch clamp system to assess compound effects on the hERG potassium channel. This high-throughput assay detects inhibitors that may prolong QT intervals and cause arrhythmias, aiding early drug safety evaluation. With precise data under physiological conditions, it supports regulatory compliance to advance safer therapeutics. 

Ultra-Precise Quantitation and Chiral Analysis, Streamlined

Unlock precision gene editing with GenScript’s complete Cas protein solutions. Explore our ready-to-use Cas9, Cas12a, Cas13a, Base Editors, MAD7, and Prime Editors- engineered for high efficiency, low off-target rates, and broad cell type compatibility. Licensed from Broad Institue, these products are available in both RUO and cGMP formats, and succesfully supported global IND applications. Need unique Cas nuclease or editors?…

Thermo Scientific Orbitrap Excedion Pro Hybrid Mass Spectrometer provides advanced performance and precision to help you achieve groundbreaking discoveries in your scientific analyses

Compact Hypoxia Workstation

Elephas Live™ Platform: Ex vivo cytokine profiling enables precision medicine

Focus on What Matters The Most

Human TNF-alpha Protein, His Tag (TNA-H5228) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the C-terminus, and has a calculated MW of 18.3 kDa. The protein migrates as 17-19 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.