Products & ReviewDrug Discovery & Development
TARGATT™ CHO K1 Kits
Applied StemCellWorldwide
Express proteins—even large and challenging constructs—and conduct screening studies directly in CHO K1 cells using efficient, reliable TARGATT™ large knock-in technology. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions) into the reliable H11 safe harbor site, TARGATT™ CHO K1 kits move you to the next inflection point faster.
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- Insert genes with confidence—with TARGATT™ technology you can achieve site-specific, single-copy, insertion of 20+ kb at the reliable H11 safe-harbor locus
- Express and screen complex constructs—20+ kb knock-in capability means you can express and screen full-length antibodies/bi-specific antibodies, synthetic circuits, multiple proteins at strict stoichiometry, and even membrane proteins
- Develop cell lines fast—with efficient, site-specific insertion at the H11 locus, you can be confident in reliable gene expression that is consistent from clone to clone—no need for clonal purification—speeding you to your next step
- Use pool-based approaches—reliable insertion and expression from the H11 locus also speeds your workflows by enabling the use of pools for variant selection or protein production
- Streamline commercialization—straightforward licensing with clear freedom-to-operate
Find a kit for your needs
- Cat.# AST-1420 for general protein expression
- Cat.# AST-1405 for general expression from the A2 safe harbor site instead of the H11 locus
- Cat.# AST-1409 for building screening libraries using FACS selection
- Cat.# AST-1410 for building screening libraries using drug selection
