Drug Discovery & Development Products & Reviews

NanoMixer is a precision microfluidic mixing platform designed for laboratory-scale preparation of mRNA, DNA, and siRNA delivery systems. It is an electrically driven, benchtop instrument that operates without the need for compressed air or hydraulic oil.

Disruptive technology for the characterization of small molecules and fragments. With enhanced sensitivity, expanded thermal options, and advanced microfluidics, the Carterra Ultra™ platform is our most sensitive instrument for interrogating multiple proteins and off-target binding in parallel.

Disruptive Technology for Screening and Characterization. Enhanced sensitivity and fast data collection rate build upon unmatched capabilities in throughput and enable assays such as TPDs/PROTAC®s, kinase, cytokines, DELs, and protein:protein inhibitors.

Twist Multiplexed Gene Fragments are double stranded gene fragment sequences of up to 500 base pairs in length that are delivered as a pool instead of one fragment per well matrix.

KREX™ i-Ome™ Discovery Services enable highly multiplexed autoantibody profiling for rapid, reproducible discovery across diverse diseases. The platform measures antibody binding to 1,800+ full-length, correctly folded human proteins – preserving conformational epitopes for highly specific and biologically relevant autoantibody detection. It provides valuable insight into immune responses in health, disease and treatment.

Lynx Certified Disposable Tips are manufactured in GMP clean-room conditions, with gamma irradiation and in-line visual QA inspection, ensuring sterility and reliability. Packaged in ANSI-standard tip boxes, they integrate seamlessly across Lynx decks—making tip handling safe, flexible, and maintenance-free.

On the Fly, Swappable, Multipurpose Tools! The Multi-Core Pipetting Arm (MCPA), Lynx offers seamless core swapping, increased throughput, and ultimate flexibility — empowering labs to do more, faster.

The AptaFluor® SAH Methyltransferase Assay Kit enables ultra-sensitive, direct detection of SAH—the universal product of methyltransferase reactions—using a riboswitch-based TR-FRET format. With no coupling enzymes required, it delivers high signal-to-background, Z’ ≥ 0.7, and is fully HTS-compatible for drug discovery and inhibitor screening.

BellBrook Labs’ Lead Discovery Services deliver expert support for hit-to-lead efforts. From inhibitor screening and potency profiling to residence-time, mechanism-of-action, and selectivity studies, their team tailors efficient enzymatic assays to your program—accelerating lead advancement with precision and flexibility.

The Transcreener® cGAMP cGAS Assay Kit offers mix-and-read fluorescent detection of cGAMP—the product of cGAS activity—with no coupling enzymes required. Available in FP or TR‑FRET readouts (far-red tracers minimize interference), it’s HTS-ready (Z’ ≥ 0.7), automation-compatible, and validated on 96‑, 384‑, and 1536‑well formats for enzyme kinetics, SAR, and inhibitor screening.

The CD73 activity assay for HTS and hit-to-lead. Measure specific activity of CD73 in a simple mix-and-read format. The kit is designed for compound library screening and follow-up inhibitor discovery.

The Transcreener dAMP Exonuclease Assay directly measures dAMP produced by exonuclease enzymes as they cleave polynucleotides. 

The Transcreener® GDP GTPase Assay Kit directly measures GDP produced during GTP hydrolysis in a homogeneous mix‑and‑read format—no coupling enzymes needed. Compatible with GTPases, GAPs, and GEFs, it supports FP, FI, and TR‑FRET readouts using far‑red tracers to reduce interference. HTS‑ready with excellent sensitivity (Z′ ≥ 0.7), it streamlines screening and profiling workflows.

Express proteins—even large and challenging constructs—and conduct screening studies directly in HEK293 cells using efficient, reliable TARGATT™ large knock-in technology. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions) into the reliable H11 safe harbor site, TARGATT™ HEK293 kits move you to the next inflection point faster.

Express proteins—even large and challenging constructs—and conduct screening studies directly in CHO K1 cells using efficient, reliable TARGATT™ large knock-in technology. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions) into the reliable H11 safe harbor site, TARGATT™ CHO K1 kits move you to the next inflection point faster.

Build tomorrow’s cell therapies and cell-based disease models using TARGATT™ Human Induced Pluripotent Stem Cell (hiPSC) Kits. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions), TARGATT™ hiPSC technology enables expression of large proteins and multi-protein complexes in hiPSC-derived human cell lines.

GenScript’s Enceed™ T cell Activation Reagent is a biocompatible, non-toxic solution designed for the in vitro activation and expansion of human T cells from PBMCs or enriched T cell populations. Utilizing nanosized particles coated with anti-CD3 and anti-CD28 antibodies, it ensures high-fold expansion with a stable memory phenotype, maintaining high cell viability for enhanced downstream applications.

HiFi sequencing within reach

The Rapid_pH™ Automated 96 pH meter automates the pH measurements of samples in a 96 well format. The Rapid_pH allows samples to be processed in a fraction of the time compared to manual methods avoiding errors in both measurement and data registration. Full automation for well plates and other arrayed containers provides unattended runs and walk-away time.

A compact benchtop design that incorporates 2 or 10 individually powered, high-output stirring stations which can prepare samples for content uniformity testing up to 90% faster than conventional methods.​

Accelerating radiopharmaceutical development in oncology

Biotinylated Human CD20 Full Length, His,Avitag (CD0-H82E3) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the C-terminus followed by an Avi tag with calculated MW of 36.9 kDa and migrates as 43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Hypoxia Workstation

RASTRUM™ Allegro is a revolutionary 3D cell culture platform designed to generate biologically relevant models at scale. It streamlines the creation of complex, structured 3D cell environments, accelerating drug discovery and disease research.

The Scorpion Automated Liquid Handler delivers precise, efficient, and cost-effective liquid handling with versatile labware compatibility and advanced automation for workflows like protein crystallization, re-arraying, and normalization. Its compact design, intuitive software, and ability to handle diverse fluid viscosities and application workflows make it an ideal choice for labs seeking to improve throughput and reproducib…