Single B Cell Sorting based Native™ Antibody Discovery Services
Creative Biolabs has proudly developed the unique Native™ Antibody Discovery Platform to develop native monoclonal antibodies using antigen-specific B lymphocytes cytometry technology.
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Creative Biolabs has developed the exclusive Native™ Antibody Discovery Platform to isolate single antigen-specific plasma cells to retrieve native antibodies with extremely high in vivo specificity and affinity.
Moreover, this new technology allows the selection of a larger number of antibody candidates at once. In addition, the selection only takes 2-3 weeks post-immunization.
It should be considered by far the most efficient way in developing native monoclonal antibodies from humans, rabbits, rats, mice, chicken and other species such as camelids, sheep, monkeys, dogs and even cows. For initiating native antibody development, single B cells need to be isolated and identified. Based on the principles used, the existing techniques can be classified into two groups, the one based on cell physical properties and the other one based on cellular biological characteristics.
Advantages
- Native paired heavy chain and light chain
- In vivo affinity maturation
- High specificity and stability in vivo
- Large pool of antibody candidates
- Competitive and affordable price
- Diverse species available
All listed services and products are For Research Use Only.
