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Carterra LSA-XT

Disruptive Technology for Screening and Characterization. Enhanced sensitivity and fast data collection rate build upon unmatched capabilities in throughput and enable assays such as TPDs/PROTAC®s, kinase, cytokines, DELs, and protein:protein inhibitors.

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The proprietary Carterra LSAXT HT-SPR technology platform expands beyond antibody discovery to enable PROTAC®s, protein-protein inhibitors, kinase, and cytokine screening and characterization. The LSAXT delivers up to 100x the data in 10% of the time and with 1% of the sample requirements of other systems and consumable costs of other label-free instruments.

The LSAXT enables the following automated workflows in single unattended runs:

  • Capture-based kinetics and affinity: Screen up to 1152 ligands
  • Coupled kinetics: Up to 384 immobilized ligands
  • Epitope binning: Interrogate up to 384×384 pairwise, competitive interactions
  • Quantitation: Measure concentration of up to 1152 samples
  • Peptide mapping: Screen up to 384 analytes against an array of up to 384 peptides
  • Blocking / neutralization assays: 384 assay capacity
  • Regeneration scouting: Scout 96 conditions in parallel
  • General multiplexed applications: Array any combination of up to 384 ligands

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