NanoMixer

GenizerNanoMixerAvailable: Worldwide

NanoMixer is a precision microfluidic mixing platform designed for laboratory-scale preparation of mRNA, DNA, and siRNA delivery systems. It is an electrically driven, benchtop instrument that operates without the need for compressed air or hydraulic oil.

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Description

NanoMixer is a precision microfluidic mixing platform designed for laboratory-scale preparation of mRNA, DNA, and siRNA delivery systems. It is an electrically driven, benchtop instrument that operates without the need for compressed air or hydraulic oil.

The NanoMixer enables programmable flow rates (0–10 mL/min per pump) and controlled mixing ratios using gastight syringes (1 mL, 2.5 mL, 5 mL, or 10 mL), with configurations available for dual (NanoMixer), triple (NanoMixer-Triplex), or quadruple (NanoMixer-Quad) component blending.

Each NanoMixer model is equipped with independent syringe pumps, a PLC control system, and mixing modules that ensure reproducible and uniform formulation. With a working pressure up to 500 psi and temperature tolerance up to 80°C, the system supports sterile, dead-volume-minimized mixing suitable for sensitive biopharmaceutical applications.

Performance Features of NanoMixer:

  • Precision Mixing: Programmable ratio and speed control with ±0.1 mL inlet accuracy
  • Modular Design: Available in 2, 3, or 4-pump configurations for dual, ternary, or quaternary blending (A+B, A+B+C, A+B+C+D). The quaternary pump configuration also supports continuous microfluidic blending of A+B by allocating two pumps for continuous feeding of component A and two pumps for component B.
  • Compact and Lightweight: Integrated design (70×36×30 cm, 20–35 kg) suitable for benchtop use
  • Thermal Tolerance: Up to 80°C (176°F) for formulation stability
  • Digital Interface: Pressure display or analog pressure gauge options
  • Easy Cleaning: Flush-to-clean system
  • Compliant: CE and RoHS certified

Brochures

Advanced lipid nanoparticle formulation and resizing solutions

Lipid nanoparticles are now central to delivering mRNA, DNA, siRNA, and emerging nucleic‑acid therapeutics, driving demand for precise, scalable formulation tools.

Discover how Genizer’s NanoMixer Microfluidic Formulation Platform meets this need with controlled, high‑pressure microfluidic mixing that produces uniform, stable LNPs with narrow size distributions. Operating up to 500 psi, the benchtop system enhances solubility, reproducibility, and scalability, supporting seamless progression from early research to larger‑scale development.

Product Overview

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