Drug discovery > Basic Research Products & Reviews

The Twist NGS Methylation Detection System provides a robust, end-to-end sample preparation solution for identifying methylated regions in the human genome. The workflow employs a unique enzymatic process from New England Biolabs® that is much less damaging to DNA, alongside Twist‘s Custom Methylation Panel design.

The Twist Bioscience MRD Rapid 500 Panel is a scalable target enrichment solution for monitoring minimal residual disease that leverages Twist’s silicon based DNA synthesis platform to design and manufacture capture panels for personalized medicine. 

The Twist UMI Adapter System enhances the detection of low-frequency somatic variants in cell-free DNA (cfDNA) by incorporating unique molecular identifiers (UMIs) during library preparation, increasing sensitivity and reducing PCR errors.

Twist's cfDNA Pan-Cancer Reference Standard v2 provides researchers with high-quality, synthetic reference materials to assess and validate liquid biopsy assays, enhancing the detection of low-frequency cancer associated variants.

High Sensitivity. High Conversion. Low-Input

Twist’s RNA sequencing workflows offer a complete NGS solution that produces uniform libraries for RNA sequencing.

GenScript’s Enceed™ T cell Activation Reagent is a biocompatible, non-toxic solution designed for the in vitro activation and expansion of human T cells from PBMCs or enriched T cell populations. Utilizing nanosized particles coated with anti-CD3 and anti-CD28 antibodies, it ensures high-fold expansion with a stable memory phenotype, maintaining high cell viability for enhanced downstream applications.

High fidelity, flexible subcellular proteomics for rapid and quantitative spatial phenotyping

Express proteins—even large and challenging constructs—and conduct screening studies directly in HEK293 cells using efficient, reliable TARGATT™ large knock-in technology. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions) into the reliable H11 safe harbor site, TARGATT™ HEK293 kits move you to the next inflection point faster.

As a pioneer in the CGT field, GenScript has developed the CytoSinct™ cell isolation platform and Enceed™ T Cell Activation reagents, leveraging its extensive experience in antibody and magnetic bead development, along with its comprehensive expertise in the CGT industry chain. We provide​ high-quality cell isolation magnetic nanobeads, activation reagents, consumables and instruments to accelerate the R&D and commercializatio…

BioIVT provides isolated exosomes from a variety of human, animal, and plant sources, as well as custom characterization and in vitro assays investigating function and potential therapeutic benefit.

BioIVT offers high quality, normal and disease state, fresh mobilized and cryopreserved leukopaks, custom collected or sourced from extensive inventory, featuring a diverse donor pool including over 600 HLA-typed recallable, consented donors near biotech hubs in the US and UK.

BioIVT’s extensive, highly characterized, normal and disease-state tissue samples are collected and prepared under strict ethical and QC policies and feature detailed clinical data as well as pathologist verification of disease tissue blocks to help ensure the accuracy of your research. Custom collections or extensive inventory are available from a diverse donor pool or any commercially available species.

Access 30+ years of BioIVT’s vast biobank collections’ clinical data, biospecimen imaging and biomarker findings. Delve into AI-ready datasets for oncology, neurology and more that meet regulatory requirements, ethical standards and privacy laws.

BioIVT is the leading provider of quality, highly characterized, ethically procured ADME research products, featuring custom preparation or extensive ready-to-ship inventory, large lot sizes and expert support.

Isolated immune cells play a crucial role across the stages of drug discovery and development from biomarker and target identification through screening and safety assessment to manufacturing. They can be used to create disease models, cell lines, gene editing techniques and more.

BioIVT has the expertise in the processes required for ethical acquisition of biospecimens that cover a wide range of disease states and the protocols needed to produce reliable data. With over 425 IRB-approved clinical sites, BioIVT provides clinical specimens for nearly all disease states.

BioIVT supplies high quality, ready to ship or custom plasma, serum, and whole blood—both normal and disease-state—collected from a diverse pool of consented donors under IRB-approved protocols or a wide variety of species.

Express proteins—even large and challenging constructs—and conduct screening studies directly in CHO K1 cells using efficient, reliable TARGATT™ large knock-in technology. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions) into the reliable H11 safe harbor site, TARGATT™ CHO K1 kits move you to the next inflection point faster.

As the world's largest private repository of human cerebrospinal fluid, BioIVT’s Center for NeuroExcellence offers 35,000+ healthy and 113,000+ diseased donor samples allowing for comparative studies and precise control matching. The samples are ethically collected following strict quality standards and feature detailed clinical data and matching blood, plasma, or sera.

Principles and Procedures for Detection and Culture of Fungi in Clinical Specimens

With decades of drug metabolism, drug-drug interactions (DDI) and related expertise, BioIVT’s experts can provide you with the right studies to understand the properties and potential risks of your compound when it’s most critical for your program.

Build tomorrow’s cell therapies and cell-based disease models using TARGATT™ Human Induced Pluripotent Stem Cell (hiPSC) Kits. With the ability to efficiently and site-specifically insert 20+ kb of DNA (more with nested reactions), TARGATT™ hiPSC technology enables expression of large proteins and multi-protein complexes in hiPSC-derived human cell lines.

Model 1575 Immunowash Microplate Washer