CyotoSinct™ Cell Isolation Nanobeads and Instruments (RUO and GMP)
As a pioneer in the CGT field, GenScript has developed the CytoSinct™ cell isolation platform and Enceed™ T Cell Activation reagents, leveraging its extensive experience in antibody and magnetic bead development, along with its comprehensive expertise in the CGT industry chain. We provide high-quality cell isolation magnetic nanobeads, activation reagents, consumables and instruments to accelerate the R&D and commercializatio…
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GenScript CytoSinct™ Nanobeads leverages decades years of expertise in antibody development and magnetic bead production to precisely isolate specific cell populations. The Nanobeads are superparamagnetic nanoparticles composed of biodegradable matrix and pre-conjugated with highly specific monoclonal antibody. They are easy to use without de-beading and offering highly efficient cell isolation from various starting materials, including PBMCs and leukopaks. The isolated target cells are highly viable and can be used for a variety of downstream applications, including cell culture, activation, expansion, flow cytometry, gene editing, and animal model transplantation, etc,. Available in both RUO (Research Use Only) and GMP (Good Manufacturing Practice) grades with a wide range of popular targets, they can be used together with both CytoSinct™ Manual Separator for research or CytoSinct™ 1000 automated instrument for manufacturing. CytoSinct™ Nanobeads are available ready-to-use for popular targets or fully customized to your specifications.The CytoSinct™ Manual Separator system is designed for the magnetic isolation of both human and animal cells and used together with superparamagnetic CytoSinct™ Nanobeads.
The CytoSinct™ Separation Column, independently developed by GenScript, is designed for use with CytoSinct™ Magnetic Rack. Its built-in ferromagnetic beads amplify the magnetic field up to 10,000-fold, creating a powerful high-gradient magnetic environment for efficient cell separation. When the column is attached to the magnet, Nanobeads labeled cells are retained within the column, while unlabeled cells flow through. After removing the column from the magnetic field, the retained cells can be gently eluted. Both cell fractions—labeled and unlabeled—are viable for downstream applications such as cell culture, flow cytometry and animal transplantation.
The CytoSinct™ 1000 cell isolation solution is an automated, user-friendly, and highly efficient system for enriching or depleting human cells. This solution utilizes CytoSinct™ Cell Separation technology, which incorporates immuno-magnetic nanoparticles to selectively isolate targeted cell populations with precision. By combining automated isolation with the sensitivity and specificity of antibody-based purification and the precision of nanoparticles, scientists can process up to 120×10⁹ total cells (full leukopak) in just 2 hours using the CytoSinct™ 1000 system. The CytoSinct™ 1000 Instrument and CytoSinct™ Nanobeads (GMP) have successfully supported global IND applications, receiving approvals from the FDA and NMPA. CytoSinct instrument is also available for integration with robotic automation system.
