Tosoh Bioscience - Separations Drug discovery > Lead Discovery Products & Reviews

“Allround“ SEC-columns for initial analysis of unknown samples

EcoSEC Elite and EcoSEC HT GPC/SEC Systems enable efficient polymer characterization

TSKgel GPC columns for organic-soluble polymers are packed with spherical particles composed of polystyrene crosslinked with divinylbenzene (PS-DVB)

Ca++Pure-HA is a hydroxyapatite resin used in the chromatographic separation of biomolecules.

TSKgel FcR-IIIA-NPR  affinity columns for direct analysis of mAb activity.

TSKgel Protein A-5PW affinity columns for direct analysis of mAb titer. 

TOYOPEARL NH2-750F offers a high binding capacity across a range of pH values and conductivities

TSKgel SuperQ-5PW is especially suited for industrial purification of oligonucleotides

TSKgel Butyl-NPR hydrophobic interaction columns for analysis of antibody-drug conjugates (ADCs) and as an orthogonal method to analyze protein aggregation, oxidation and deamidations.

The TSKgel DNA-NPR weak anion exchange column is designed to analyze nucleic acids. It routinely separates plasmid isoforms, PCR products and oligonucleotides.

TSKgel Amide-80 and TSKgel NH2-100 HILIC columns from Tosoh Bioscience are first class columns when it comes to separations of hydrophilic compounds like peptides, carbohydrates, polar natural substances, amino acids, oligonucleotides, organic polar acids and bases, even proteins.

HPLC column

Widely considered the premium columns for analyzing biopolymers by GFC, TSKgel G2000SWXL, 5 μm columns are an excellent choice for small proteins and peptide separations.

The TSKgel Alpha-4000 column is packed with rigid, porous polymer beads which show minimal shrinkage or swelling in polar organic solvents (methanol, acetonitrile, DMSO, isopropanol, THF, and HFIP). This column is stable in a wide variety of organic solvents at concentrations up to 100%.

The TSKgel OligoDNA RP and TSKgel TMS-250 columns incorporate 5 μm or 10 μm spherical porous silica with 250Å pores to allow unhindered access by large oligonucleotides and proteins respectively.

TSKgel STAT columns were designed to increase throughput for high efficiency separations of biomolecules. The nonporous, hydrophilic base material provides superior performance at reduced analysis time.

TSKgel SW-type columns for size exclusion/gel filtration analysis of antibodies and other proteins are silica-based. A hydrophilic diol-type bonded phase shields the silica surface from interacting with protein samples.

TSKgel Protein C4 is a reversed phase HPLC column for the separation of intact proteins.

TSKgel mAb SW SEC Columns – Setting new Benchmarks for Antibody Analysis.

TSKgel UP-SW Series offers highest resolution based on established SEC technology.

TOYOPEARL AF-rProtein L affinity resin for the capture of mAbs and mAb fragments 

TOYOPEARL Sulfate-650F offers a high binding capacity for IgG across a range of pH values and conductivities

The TSKgel UP-SW3000-LS UHPLC column analyses biotherapeutics by size exclusion chromatography and is designed for the combination with MALS and MS.

Octave BIO intensifies your downstream processing productivity

SkillPak 50 (2.5 cm ID x 10 cm L, CV 50 mL) and 200 (5 cm ID x 10 cm L, CV 200 mL) pre-packed columns offer a reproducible and efficient solution for developing purification methods for biomolecules. They are the best solution to scale up methods developed on SkillPak 1 and 5 mL pre-packed columns.