TruScan RM with TruTools
The Thermo Scientific™ TruScan™ RM Handheld Raman Analyzer delivers reliable material identity verification through sealed packaging in seconds, right at the point-of-need. With the Thermo Scientific TruTools™ embedded chemometrics package, users can build advanced, customized qualitative and quantitative methods for complex material analysis problems.
TruScan RM and TruTools embedded chemometrics
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Outstanding performance within negligible time.
Analytical
A must have tool for laboratories who wish to have optimum efficiency, with innovative technologies.
Review Date: 8 Feb 2021 | Thermo Fisher Scientific
Amazing analytic tool due to is small weight and its transportability.
Research & developement
We use our handheld raman analyzer to monitor in-situ the kinetic behavior of several of our developments. Among them, polymerization processes and nanomaterials production. The small footprint and its transportability is especially important.
Review Date: 24 Dec 2020 | Thermo Fisher Scientific
Easy identification possible from each container of raw materials in pharma area.
Pharma
High quality, robust equipment, easy handling, easy identification possible from each container of raw materials in pharma area.
Review Date: 26 Oct 2020 | Thermo Fisher Scientific
Less is more.
Pharmaceuticals
Easy to implement, easy to use, easy to show. Less time spent sampling, less time spent on analysis, less time spent in the product value chain.
Review Date: 20 Jan 2020 | Thermo Fisher Scientific
Great instrument, we have saved a lot of money and time on external analysis.
ID of raw material for the pharma industry
Really easy to use, analysts can use it with little training, results have been reliable for the 2 years we have had the TruScan, minimun maintenance and no need to buy standards.
Review Date: 22 Jul 2019 | Thermo Fisher Scientific
The Thermo Scientific TruScan RM Raman overall is an excellent analytical device
Pharmaceutical
The Thermo Scientific TruScan RM Raman handheld device is easy to use overall. Additionally - analytical results are reproducible and efficient! Being able to reduce cycle times from testing/release is very important from a customer basis. One 'user friendly' improvement that could be made is to offer the ability to connect an external keyboard that would be possible with the addition of a USB port.
Review Date: 19 Jul 2018 | Thermo Fisher Scientific
The TruScan RM analyzer includes state-of-the-art optics paired with a patented multivariate residual analysis that offers an effective chemometric solution for material identification, with two spectral pre-processing options. The analyzer’s non-destructive point-and-shoot sampling principle facilitates rapid verification of a broad range of chemical compounds, including cellulose-based products.
The TruScan RM analyzer with TruTools becomes a more powerful spectrometer. Applications for QA/QC include enhanced raw material ID for similar compounds, multiple component ID, and identification and quantification of finished products. In PAT, applications include at-line endpoint determination for distillations, reaction monitoring, and powder blending operations.
TruTools leverages Solo, a chemometrics software package from Eigenvector Research Inc. that allows users to develop models that can be deployed onto the TruScan RM analyzer.
Features:
- Weighs less than 2 lbs (0.9kg)
- Rugged design; chemical and drop resistant
- Enhanced 21 CFR Part 11 and cGMP compliance with biometric login, complex password options and full audit trail features
- Noncontact analysis through plastic bags, glass containers, blister packs and clear gel caps
- Intuitive workflow adapted to production environment through PDF batch reports and ease of data input using barcode scanner
- Easy fleet management feature enables cloning of instrument and identification methods
- Suitable for screening falsified and sub-standard medicines
- Qualification documentation (IQ/OQ/PQ) and standard operating procedures available
Brochures
Process monitoring from raw materials to finished products in biopharma
As part of current good manufacturing practice (cGMP), many pharmaceutical manufacturers are adopting process analytical technologies (PAT), quality by design (QbD), or process validation (PV) to provide continuous process verification and analysis. Analytical instruments may be used for at-line and in-process monitoring to bring the technology to the sample to speed up the analysis process and enable more flexibility from a smaller footprint. Discover efficient process monitoring solutions in biopharmaceutical production with Thermo Scientific analyzers and bioreactors.
Probabilistic evaluation – First principles vs. empirical
Explore the fundamentals and performance characterization of the Thermo Scientific™ TruScan™ Handheld Raman Analyzers. Discover what makes this analyzer unique and learn how you can put the power of spectroscopy into the hands of new users, without extensive training.
Probabilistic approach for material verification and identification in pharmaceutical applications
Spectroscopic material verification is a critically important analytical application within the pharmaceutical industry because of the adoption of standards such as the Pharmaceutical Inspection Co-operation Scheme (PIC/S), Annex 8. PIC/S Annex 8 requires that individual samples be taken from all incoming containers and an identity test be performed on each sample. Individual container identity testing puts drastically higher demands on expert analysts’ time.
Discover how Thermo Scientific™ TruScan™ Handheld Raman Analyzers use advanced processing during both data collection and analysis to ensure that sound statistical judgment supports every material-verification decision. They can enable nonexperts to positively verify the identity of materials at the point of receipt, increasing an organization’s throughput and cycle time.
How to Verify 3 Different Opadry Whites Using a Handheld Raman Analyzer
In this application note, learn how TruScan RM with TruTools is used to analyze a number of Opadry film coatings that are widely used by pharmaceutical manufacturers.
Stearates Verification Using a Handheld Raman Analyzer
Magnesium stearate, calcium stearate, and zinc stearate are frequently used in the pharmaceutical industry as lubricants for capsules and tablets, but share a similar chemical structure which makes them challenging to verify. In this application note, various stearates were successfully identified by utilizing a customizable principle component analysis (PCA) method on the Thermo ScientificTM TruScanTM RM Handheld Raman Analyzer.
Opadry Verification Using a Handheld Raman Analyzer
The TruScan RM analyzer provides manufacturers with fast and accurate material verification, minimizing the need for time-consuming laboratory sampling tests. In this application, a Principal Component Analysis (PCA) method was found to be successful in identifying Opadry orange from Opadry green.
Analytical Methods for Field-Based Material Identification and Verification
Current field-based chemical identification instruments for pharmaceutical applications typically use one of three analytical methodologies: hit quality index (HQI), traditional chemometrics, or the Thermo Scientific probabilistic approach. This white paper compares HQI and the Thermo Scientific probabilistic approach, leaving the comparison between probability and traditional chemometrics to a separate white paper.
Specialized Identification and Analysis of Raw Materials with TruScan RM Handheld Raman Analyzer
Thermo Scientific portable solutions delivers specialized identification and analysis of raw materials for the highly regulated global pharmaceuticals industry.
Lean manufacturing practices with Raman spectroscopy for biopharmaceutical production
Watch this on-demand webinar to learn more about the implementation of Raman spectroscopy for final product identification
The Handheld Raman Technology Ensuring Biopharmaceutical Quality, from Start to Finish
Discover the handheld Raman spectroscopy analyzer advancing biopharmaceutical material identification
