Prometheus NT.Plex for high throughput protein stability by NanoTemper Technologies

Manufacturer NanoTemper Technologies  |  Available Worldwide
Prometheus NT.Plex is a capillary chip-based instrument that measures the thermal stability and turbidity of a protein sample using dye-free nanoDSF (nano Differential Scanning Fluorimetry) technology. Use only 10 μL of sample to efficiently obtain high-resolution data that enables you to make better decisions about your development candidates.


Prometheus NT.Plex for high throughput protein stability by NanoTemper Technologies product image
Prometheus NT.Plex for high throughput protein stability
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The Prometheus NT.Plex measures thermal unfolding and turbidity in parallel using near-UV detection systems. With nanoDSF and backreflection technologies, researchers can make better decisions about the stability of their protein formulations while using small volumes of sample. The NT.Plex is designed for more efficient sample handling using chip-mounted capillaries, which easily load samples from a 384-well plate. It is an ideal addition to any lab interested in thermal shift assays, profiling mutant protein behavior, or formulating storage and assay buffers.

Key Features:

  • Label-free measurements in solution
  • Broad concentration range, as low as 0.02 mg/ml to >200 mg/ml protein
  • Measure intrinsic fluorescence of your proteins with dual UV system: 330 nm and 350 nm fluorescence detection
  • Monitor amorphous protein aggregates with near-UV turbidity detection
  • Capillaries hold 10 μl of sample; measure up to 24 samples at a time with capillary chips, designed to quickly load sample from a 384-well plate
  • nanoDSF parameters: Tm, Tonset, reversibility of unfolding
  • Backreflection parameters: Tturbidity (onset of turbidity, particles >12.5nm in radius)
  • Temperature range: from 15 °C to 95 °C (up to 110 °C with High Temperature Upgrade)
  • Upgrade your instrument with software for chemical denaturation measurements (G, c50) or complex thermal cycling ramps (isothermal, temperature cycling, stepped increments)
  • Maintenance-free instrument
  • CFR 21 Part 11 compatibility
  • Straightforward handling: simple sample preparation and intuitive software user interface
     

Product Overview

Prometheus NT.Plex for high throughput protein stability by NanoTemper Technologies product image

Prometheus NT.Plex for high throughput protein stability

Manufacturer NanoTemper Technologies  |  Available Worldwide

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