Member since: 2015
Organization: Antidoping laboratory-FMSI
Easy to obtain very clean extract
Application Area: Purification of urine samples
"The Oasis cartridges are very easy to use, robust and reproducible. The selection of an appropriate purification protocol increases the specificity leading to a very clean extract."
Member since: 2018
Great results. Would certainly use this product again in other applications as well.
Application Area:Purification of metabolites from cell media
"The Oasis µplate was used as sample preparation for LC TOF application in order to get a valid concentration determination. The product was very easy to use and produced reliable results and good quality."
Member since: 2018
Organization: WSU College of Pharmacy and Pharmaceutical Sciences
Good results. Effective.
Application Area:Solid phase Extraction of biological samples to concentrate the metabolites
"The PRIME HLB microElution Plate is a great apparatus for the Solid Phase Extraction technique. I used it to concentrate my metabolites of interest in rat urine samples, and it worked perfectly. But, it didn't work as effectively while concentrating the same metabolites in mice plasma samples. I believe the reproducibility across species (rats vs mice) and the kind of biological samples (plasma vs urine) is low. I would like to see better optimization of the apparatus."
Member since: 2017
Organization: Vermont Forensic Laboratory
Excellent analytical results and ease of use.
Application Area:Sample preparation for analysis of THC and metabolites in whole blood from impaired drivers
"After evaluating many of the SPE products currently on the market on the criteria of recovery, matrix cleanup, ease of use, and cost, Oasis PRiME HLB uElution plate by far is the best option for the analysis of drugs of abuse in whole blood samples. Waters provided excellent support through application notes, in-person training and method development, troubleshooting, and equipment support throughout the optimization and validation process. The uElution plates demonstrate excellent reproducibility, recovery, and matrix cleanup, even with a complex matrix such as whole blood. The 96-well plate form factor will support a lot of scalability for our lab as we receive additional samples, and the Waters positive pressure manifold makes sample processing extremely easy and rapid. Overall, a great system for tricky analytes and matrices!"
Member since: 2017
Great results and good limit of detection
Application Area:Metabolites in urine samples
"We are using the Oasis HLB µElution Plate 30µm for our Porphobilinogen analysis in urine and the Oasis MCX µElution plate for our LysoGb3 analysis in urine, on our metabolic lab. We have a manifold voor the extraction system, also from Waters. We use it to concentrate the components to detect them on our Waters Micromass Quattro Micro. We are performing this analysis for a few years now and it gives great results for us. The lysoGb3 analysis is in nmol/l. So the limit of detection is very good for us. We had a private workshop on our lab by some employees from Waters to show us how it all works. So we are satisisfied with it! The plates are not cheap, but they work for us!"
The Oasis® uElution plate format combined with the Oasis chemistries allow elution volumes as low as 25uL, eliminating the time consuming evaporation step, producing very clean extracts with a 5 to 10 fold increase in concentration.
The Oasis® family of sample extraction products is designed to simplify and improve your sample preparation by combining the right sorbent chemistry, device format and methodology. Achieve robust, selective, and sensitive solid-phase extraction [SPE] methods without worrying about low recoveries caused by breakthrough, sorbent drying, pH limitations, and undesirable silanol activity.
Oasis® SPE sorbents—covered by eight U.S. patents—are unique in their purity, reproducibility, stability, and retention characteristics. Today, they are the most widely used polymeric SPE products in bioanalytical laboratories.