N SIM-E Super-Resolution Microscope System by Nikon Instruments

Manufacturer Nikon Instruments  |  Available Worldwide
N-SIM E is a streamlined, affordable super-resolution system that provides double the resolution of conventional light microscopes. Combining N-SIM E and a confocal microscope allows the flexibility to select a location in the confocal image, and easily switch to view it in super-resolution, enabling the acquisition of more detail. Features The N-SIM E nearly doubles the spatial resolution of conventional light microscopes, enabling detailed visualization of minute intracellular structu... Read more


N SIM-E Super-Resolution Microscope System by Nikon Instruments product image
N SIM-E Super-Resolution Microscope System
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N-SIM E is a streamlined, affordable super-resolution system that provides double the resolution of conventional light microscopes. Combining N-SIM E and a confocal microscope allows the flexibility to select a location in the confocal image, and easily switch to view it in super-resolution, enabling the acquisition of more detail.

Features

  • The N-SIM E nearly doubles the spatial resolution of conventional light microscopes, enabling detailed visualization of minute intracellular structures and their interactions
  • N-SIM E provides fast imaging performance, with a time resolution of approximately 1 sec/frame, effective for live-cell imaging
  • Super-resolution images can be acquired with a larger field of view, enabling very high throughput reducing the amount of time and effort required to obtain data
  • The 3D-SIM mode generates structured illumination patterns to deliver a two-fold improvement in lateral and axial resolutions. ‘Slice’ and ‘stack’, are available to optimize results 
  • N-SIM E can be combined with a confocal microscope such as the A1 or C2+ for seamless switching between imaging modalities for multi-scale experiments
  • The dedicated compact LU-N3-SIM laser unit is installed with the three most commonly used wavelength lasers, enabling super-high resolution imaging in multiple colours
  • A full range of objectives is available: silicone immersion objectives for improved photon collection capability and resolution, a 100X oil immersion type, which is suitable for the imaging of fixed samples, or a 60X water immersion type, which is optimal for time-lapse live-cell imaging. In addition, the N-SIM E is compatible with dry objectives, making both super-resolution imaging and confocal imaging available without switching lenses