Status:
Reviewer
Member since: 2022
Organization: PLA Rocket Force Characteristic Medical Center
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- Ease of use
- After sales service
- Value for money
Good job
Application Area: cell toxicity assay
"It's easy to use in the cell toxicity assay. The results are similar to the CCK-8 assay. However, it need more cells to seed in the plates."
Review date: 30 Mar 2022 | Maestro Z
Status:
Reviewer Member since: 2021
Organization: Emory University
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- Ease of use
- After sales service
- Value for money
Great results!
Application Area:Cancer Immunology
"Quantitative data with a convenient mobile app. The Maestro Z provides a quantitative measurement of CAR-T cell-mediated cytotoxicity. The system is very easy to use, and it's powerful to see CAR-T cell killing profiles over time. The number of experiments you can run continuously with majority hands-off time is incredible. The mobile app is also great for making decisions about when to come into the lab when to add effectors, and so on."
Review date: 13 Dec 2021 | Maestro Z
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Reviewer Member since: 2020
Organization: Georgia State University
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- Ease of use
- After sales service
- Value for money
Excellent machine, excellent company.
Application Area:SARS-CoV-2 Research
"We are a lab studying SARS-CoV-2, so we were very pleased with how easy it was to install the Maestro Z system in our BSL3 lab and start collecting data the same day. Setting up experiments is quite straight forward with the plate map editor that allows you to design concentration response curves in a few clicks. This along with the new Maestro Z App that allows tracking of my experiments on my smartphone makes for a very nice user experience. The Maestro Z assay is very sensitive allowing us to detect virus-induced effects within 24 hours after infection, much faster than a plaque assay. We also appreciate that the machine provides kinetic results with very fine resolution allowing us to watch as the infection progresses over time. Finally, the customer support we have received from Axion has been nothing short of exceptional."
Review date: 31 Aug 2020 | Maestro Z
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Reviewer Member since: 2020
Organization: University of Georgia
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- Ease of use
- After sales service
- Value for money
Sensitive data on an easy-to-use system.
Application Area:Immuno-oncology assays
"The Maestro Z was incredibly easy to use, and demonstrated sensitive, real-time measurements of brain cancer cell proliferation and T cell cytotoxicity. The product is easy to set up in the laboratory space due to the convenient size and the independence from needing to place it inside an incubator. The software is very user friendly and allows for monitoring results as they occur as well as simple analysis upon completion."
Review date: 14 Jan 2020 | Maestro Z
Status:
Reviewer Member since: 2019
Organization: University of Georgia
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- Ease of use
- After sales service
- Value for money
User-friendly and powerful platform
Application Area:Analyze cancer cell proliferation and migration
"We found the Maestro Z to be extremely user-friendly with simple, yet powerful software. The setup was also easy and non-disruptive to other work since it does not require any space in the incubators. The system is very sensitive, detecting subtle differences in breast cancer cell migration to provide quantitative data for our work that was not as easily obtained with other methods. This is a great system for easily monitoring cell behavior in real-time."
Review date: 20 Dec 2019 | Maestro Z
Axion BioSystems’ Maestro Z platform uses noninvasive electrical impedance for real-time, continuous, label-free monitoring of your cells. Cell-based assays enable rapid evaluation of human biology in vitro, with substantial advantages in throughput and cost over tissue or animal models. However, many cell-based assays are endpoint assays, limited to a single snapshot in time. The Maestro Z platform’s real-time data reveals the kinetics of cell-cell interactions and cell-drug responses for better mechanistic understanding without the time- and cost-intensive process of repeating multiple endpoint assays. Over minutes or weeks, gain unprecedented access to your biology. Perfect for tracking immune cell-mediated killing, measuring cell proliferation and viability, studying the dynamics of cytotoxicity, and monitoring GCPR-mediated signaling, the Maestro Z platform delivers an easy-to-use, compact cellular analysis system suitable for any lab.
SYSTEM FEATURES
- CONTINUOUS CELL MONITORING - 96 simultaneous live recordings from your cells. Now you can track cell proliferation, morphology, and viability in real-time, even when you are out of the lab.
- SEE YOUR CELLS - Sometimes you just want to look at your cells under a microscope. Maestro Z’s 96-well plates have a viewing window in each well which allows cell visualization.
- PRECISE ENVIRONMENT - No need for an additional cell culture incubator, saving valuable lab space and money. Maestro Z’s smart environmental chamber finely controls temperature and CO₂ while rejecting electrical noise and mechanical vibrations.
- “ONE BUTTON SETUP” - Temperature and CO₂ levels automatically adjust on plate docking. Plate usage is logged via an integrated plate barcode scanner for convenient experiment tracking.
- POWERFUL DATA ANALYSIS - AxIS Z simplifies the setup, execution and analysis of your experiments. Now you can focus on the science rather than the data analysis.
APPLICATIONS
- IMMUNO-ONCOLOGY - Want to evaluate killing kinetics of immune cells such as natural killer (NK) cells or cytotoxic T lymphocytes (CTL) with physiologically relevant effector cell to target cell ratios? Concerned about the possible confounding effects of labeling your cells? Track immune cell-mediated killing label-free and in real-time with Maestro Z.
- CELL PROLIFERATION & VIABILITY - Endpoint cell assays limit your findings to a single snapshot in time. The Maestro Z platform, however, uses impedance-based cell analysis for real-time, continuous, label-free monitoring of your cells. Reveal the kinetics of cell-cell interactions and cell-drug responses for improved mechanistic insights of your cell model.
- CELL SIGNALING - GPCR binding results in conformational changes and downstream responses that can be measured by impedance. These small changes often occur rapidly, but can last minutes to hours with significant physiological consequences. The Maestro Z impedance assay allows you to sensitively and continuously measure the dynamics of cell signaling over minutes to hours without disturbing the cell biology.
Product Overview
