ResourceDrug Discovery & Development
Real-time, label-free assessment of HER2-targeted antibody-drug-conjugate therapies
2 Mar 2026Antibody-drug conjugates (ADCs), particularly those targeted toward the tumor antigen HER2, have emerged as a popular and effective treatment for cancer patients.
Discover how the effectiveness of ADC therapies in early development were assessed using the Maestro Z™, and how this instrument uses electrodes embedded at the bottom of the well to measure this process in real time so researchers can reveal the precise kinetics of ADC cytotoxicity.
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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Antibody Drug ConjugatesOncologyThe branch of medical science that deals with the diagnosis and treatment of cancer is known as oncology.