GadoSpin D is a dendritic gadolinium-based contrast agent of intermediate molecular weight specifically formulated for preclinical magnetic resonance imaging (MRI).
It is a contrast agent of high relaxivity increasing the signal intensity in T1-weighted MRI due to a shortening of the spin-lattice relaxation time (T1).
Upon intravenous injection, GadoSpin D remains within the vascular system. Significant extravasation can be observed in fenestrated blood vessels of inflamed tissue or tumors.
GadoSpin D is mainly excreted via glomerular filtration (kidneys).