Products & ReviewSpectroscopy

Crystalline PV/RR

Access crystallization and formulation information at mL scale with the new Crystalline PV/RR

Technobis Crystallization Systems

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Description

Access crystallization and formulation information at mL scale with the new version of Crystalline PV/RR, launched in November 2022.

Designed by scientists, for scientists, the new Crystalline PV/RR features:

  • AI-based image analysis
  • Improved optics with resolution up to 0.63 microns per pixel
  • Advanced analytical features
  • Ready for robotic integration

Applications:

  • Crystallization process optimization
  • Form & habit control
  • Particle size determination
  • Formulation process optimization
  • Stability of liquid formulations
  • Solubility determination
  • Polymorph, salts, cocrystals

With the new Crystalline PV/RR, every picture tells your story.


Measuring secondary nucleation through a single crystal seeding approach

Crystallization is a common process in the pharma industry in the manufacturing of solid form doses. In this application note, Technobis Crystallization Systems introduces its novel, single crystal seeding procedure for measuring secondary nucleation. This promises to allow the rapid development of industrial crystallization procedures and facilitate a deeper understanding of the crystallization process.





Application NoteSpectroscopy

Physical stability of agrochemical formulations and observation of eutectics

Physical stability of formulations is an important parameter during formulation development, especially when testing multiple phase systems (suspensions or emulsions). In this application note, Dr. Martin Viertelhaus from BASF SE, explains the essentials of physical stability of formulations, covering topics such as stability testing, observation of eutectics and how the Crystalline instrument can be used to obtain this information.


Application NoteLife Sciences

Solubility: Importance, measurements and applications

This application note covers two dynamic methods for effective and reproducible solubility data generation: the temperature variation and solvent addition methods. These methods can be easily applied by making use of the turbidity probes integrated in the Crystal16 and particle viewer cameras of the Crystalline instruments.




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