Corning® Supersomes™ P450 Inhibition Kit CYP2C9/MFC, 1/Case by Corning Life Sciences

Kit Components:• CYP2C9 + P450 Reductase + Cytochrome b5• Control: Insect Cell Membrane Protein• Buffer Solution: 0.5 M Potassium Phosphate (pH 7.4), filter sterilized• Stop Solution: 0.5 M Tris Base, filter sterilized• Cofactors: 1.3 mM NADP+, 66 mM MgCl2, and 66 mM Glucose 6-Phosphate• Glucose 6-Phosphate Dehydrogenase: 40 units/mL in 5 mM Sodium Citrate Buffer (pH 7.5)• MFC (7-Methoxy-trifluoromethylcoumarin): Fluorescence substrate, 5.5 mg• SFZ (Sulfaphenazole): CYP2C9 selective positive con... Read more


Corning® Supersomes™ P450 Inhibition Kit CYP2C9/MFC, 1/Case by Corning Life Sciences product image
Corning® Supersomes™ P450 Inhibition Kit CYP2C9/MFC, 1/Case


0 Scientists have reviewed this product


Write the First Review

No Reviews

Kit Components:
• CYP2C9 + P450 Reductase + Cytochrome b5
• Control: Insect Cell Membrane Protein
• Buffer Solution: 0.5 M Potassium Phosphate (pH 7.4), filter sterilized
• Stop Solution: 0.5 M Tris Base, filter sterilized
• Cofactors: 1.3 mM NADP+, 66 mM MgCl2, and 66 mM Glucose 6-Phosphate
• Glucose 6-Phosphate Dehydrogenase: 40 units/mL in 5 mM Sodium Citrate Buffer (pH 7.5)
• MFC (7-Methoxy-trifluoromethylcoumarin): Fluorescence substrate, 5.5 mg
• SFZ (Sulfaphenazole): CYP2C9 selective positive control inhibitor, 0.0094 mg
• HFC (7-Hydroxytrifluoromethylcoumarin): Metabolite standard (0.25 mM in 0.1 M Tris-pH 9.0)

Note:
• Freeze/thaw stability: This CYP2C9 inhibitor screening kit was subjected to 10 freeze/thaw cycles without a change in IC50 value for sulfaphenazole or a significant loss of signal to noise
• xx= Actual values can be found on the data sheet accompanying each shipped product

Product Overview

Corning® Supersomes™ P450 Inhibition Kit CYP2C9/MFC, 1/Case by Corning Life Sciences product image

Corning® Supersomes™ P450 Inhibition Kit CYP2C9/MFC, 1/Case

Manufacturer Corning Life Sciences

Be the first to review this product