Products & ReviewSeparations

SecurityGuard™ PREP Guard Cartridge System

Extends UHPLC, HPLC, SFC, and PREP column lifetime

Phenomenex Inc

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Average Rating 4.5

|2Scientists have reviewed this product

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Highly reproducible

 

Average Rating 4.7

Application Area:

Analyze bulk samples

Improves sample analysis and also improves on time.

Review Date: 1 Oct 2021 | Phenomenex Inc

Great equipment for HPLC!!

 

Average Rating 4.3

Application Area:

Analyze unknown compounds

Prep guard cartridge m is excellent,

Review Date: 1 Oct 2021 | Phenomenex Inc

A common cause of high backpressure, split peaks, broad peaks, baseline noise, baseline drift, and loss of resolution is contaminants.

All mobile phases contain some chemical contaminants or micro particulates, from the sample, solvent, or wear on the polymeric seals of the pump or injector. These contaminants can clog frits, irreversibly bind to columns, degrade performance, and even damage the flow cell. An easy solution, SecurityGuard is a universal column protection system designed to effectively (and inexpensively), protect your valuable columns, from the damaging effects of chemical contaminants, without altering your chromatographic results.

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Application NoteSeparations

Improving Preparative HPLC Column Lifetime in High-Throughput Open-Access Purification Environments

When subjected to viscous samples under high-speed chromatographic conditions, the media bed of the column may deteriorate. This application note describes the use of Axia column technology to eliminate column voiding or chanelling, in conjunction with the SecurityGuard PREP system that protects the column from contaminants and particulates. This work demonstrates the dramatic increase in column lifetime achievable with these systems in place, even when operating under high flow rate, high-pressure conditions.

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