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Malvern PanalyticalAvailable: Worldwide

Gold standard protein stability analysis for research applications

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Average Rating 4.7

|2Scientists have reviewed this product

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Great results, basic equipment for our lab, we love it.


Average Rating 4.3

Application Area:

Analyzing biotechnological proteins

We're very happy to have an instrument like this, the results and usage are very user friendly. It's not for everyday use in the lab, but we've a method where this equipment is essential. We also have the experience of having a Malvern nano Zetasizer that we love too

Review Date: 15 Jan 2021 | Malvern Panalytical

Manufacturer's Response

Thanks you for your review, so glad to hear that you have several of our products that you use every day in your lab.

Great instrument. Good-quality results.


Average Rating 5.0

Application Area:

Protein biophysics

This is a great instrument to achieve high-quality data. Both the instrument and the packaged software are user-friendly. Easy to learn, easy to use.

Review Date: 5 Jul 2019 | Malvern Panalytical

Manufacturer's Response

Thank you, we put a lot of emphasis on ‘the ease of use’ of the instrument during the development. It is gratifying to hear that you think we have made some progress in that area. Thanks again.

The MicroCal PEAQ-DSC system provides highly sensitive, easy-to-use microcalorimetry that helps reduce the time and cost associated with stability testing and comparability analysis. The MicroCal PEAQ-DSC is a manual instrument with a cleaning device, which can be upgraded to an automated version upon request.

Data generated by the MicroCal PEAQ-DSC provides critical guidance for biopharmaceutical development in protein engineering, (pre)formulation development, process development, manufacturing change control and biosimilarity and biocomparability studies. The integrated software streamlines workflows, facilitates non-subjective data analysis, performance qualification and compliance with 21 CFR Part 11 and Annex 11 regulations, all delivering high integrity data and driving productivity in biopharmaceutical research.

Key Features:

  • Gold standard stability-indicating technique requiring minimal assay development
  • Direct and label-free measurement of biomolecular native-state stability in solution
  • Measurement of very tight binding constants, up to 1020M-1
  • Manual system with pipette and cleaning device
  • Powerful MicroCal PEAQ-DSC software minimizes typical data analysis time and includes:
    • PEAQ-Compliance: The system is available with Malvern Panalytical Access Controller (MAC) to limit access to user-defined SOPs and data analysis features. Data can be displayed using the Report Generator with user details and the ability to sign using electronic signatures to facilitate the integration of the workflow into your company’s quality system and aid compliance with 21 CFR Part 11 and Annex 11 regulations. This is provided as an optional accessory
    • PEAQ-Performance: Automatically detects and validates system readiness for optimal performance
    • PEAQ-Smart (including PEAQ-Finder): For SOP-based operation and data analysis. Provides new algorithms to detect even subtle peaks and shoulders, facilitating the automatic, non-subjective identification of multiple transitions, such as those seen in multi-domain proteins
    • PEAQ-Compare: For the quantitative comparison of DSC traces for comparability studies, ideal for batch-to-batch and biosimilarity studies
    • Network-ready: email updates sent during the analysis to keep you informed of assay progress

Product Overview