Lux™ Chiral LC & SFC Columns
Polysaccharide Chiral HPLC and SFC Columns at a Very Affordable Price. Optimize your chiral separation and chiral purification with Lux® polysaccharide chiral HPLC columns. The Lux family of amylose and cellulose chiral selectors provides a variety of complementary selectivities that allow you to screen for the most effective chiral separation under Reversed Phase, Polar Organic, Normal Phase, and SFC conditions. With numer…
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Of course, it's a must buy product if you are looking at chiral separation.
Analysis of optically active compounds
Lux Chiral columns are for HPLC and SFC, and are a wonderful product from Phenomenex. Many different enantioselective phases (Chiral stationary phases) with good selectivity are available and hence efficient chiral separation is an attractive feature and one of the best reasons to choose this brand. Almost 100% of chiral screening is successful in one or other chiral stationary phases. These columns separate enantiomers and stereoisomers as well. Very rough use is possible as the stationary phase is stable in almost any solvent. It is just a gift for any analyst because one can use these columns in both phases, reverse phase as well as for normal phase with a proper switch over procedure. This is possible only due to the special coating of base silica which makes the chiral stationary phase stable at any pH. Even though frequently used in both (reverse and normal) phases, these columns give the best performance for a long time if handled and maintained systematically. This is my own experience. Another factor is a very competitive 'price' for which every purchaser is always looking. Lux Chiral columns are the best performing product at a much more reasonable cost (almost 40-45% less than other brands of chiral columns). Really a 'must buy' product for analyst working on chiral compound separations.
Review Date: 16 Jul 2020 | Phenomenex Inc
I would not recommend the Amylase chiral column Lux for Isomer separation. Phenomenex is a great company and I was surprised this product did not perform
Residue and Metabolism Chemistry for the analysis of pesticides
This product left much to desire. it did not perform as expected and did not provide the separation we had been promised or anticipated
Review Date: 23 Jun 2016 | Phenomenex Inc
Manufacturer's Response
“Hi Christopher, Thank you for reviewing our Lux Chiral LC & SFC Columns. We are sorry to hear that the column did not perform adequate separation for your analysis. We understand that chiral LC can be extremely challenging which is why we offer free chiral screening services. We would love to invite you to work together with our dedicated PhenoLogix Application Development group to find the best chiral phase for your separation. Our chiral screening has a hit ratio of more than 90% with a fast turnaround to ensure you do not lose precious analysis time. Your Technical Consultant, along with our expert Technical Team, will be contacting you shortly to help find a solution that fits your needs. You may also reach out to our technical support team directly or use our new live-chat platform, also available on our website! Please do let us know if there is anything else we can do to help.”
Polysaccharide Chiral HPLC and SFC Columns at a Very Affordable Price. Optimize your chiral separation and chiral purification with Lux® polysaccharide chiral HPLC columns.
The Lux family of amylose and cellulose chiral selectors provides a variety of complementary selectivities that allow you to screen for the most effective chiral separation under Reversed Phase, Polar Organic, Normal Phase, and SFC conditions. With numerous publications in peer reviewed journals and countless applications being developed, Lux chiral HPLC columns are rapidly becoming the premier choice for simplified chiral purification and chiral separation worldwide.
Column Details:
- Phase: Amylose-2, Cellulose-1,2,3,4
- Particle Size: 3, 5, 10, 20 µm
- Pore Size: 1000 Å
- Length: 50, 100, 150, 250 mm
- ID: 2.0, 4.6, 10.0, 21.2, 30.0, 50.0 mm
Simplified Chiral HPLC/SFC Column Screening Strategies
Demystify chirality with Lux LC & SFC Chiral Columns from Phenomenex.
Frequently Asked Chiral Questions
5 frequently asked questions about Lux® Chiral Columns.
Demystifying Chirality - Lux i-Amylose-3 Screening Application Notebook
The i-Amylose-3 chiral selector is a complementary but distinct chiral selectivity in comparison to i-Amylose-1 and i-Cellulose-5. It combines the 5-position methyl group of the i-Amylose-1 chiral selector with electron-withdrawing potential of the i-Cellulose-5 3-position chlorine group. Combined with the strong solvent flexibility of the immobilization process the Lux i-Amylose-3 column broad enantioselectivity promotes greater chiral separation success.
Chiral Separation of Atomoxetine and its S-Enantiomer on Lux® i-Cellulose-5 Column
This technical note reports on the enantiomeric separation of Atomoxetine and its S-enantiomer using the immobilized polysaccharide-based chiral stationary phase Lux i-Cellulose-5. This method can be used to evaluate the chiral purity of drug product Atomoxetine.
Chiral Separation of Naproxen by High Performance Liquid Chromatography on Lux® i-Amylose-1
This technical note reports the chiral separation of racemic Naproxen using the immobilized polysaccharide-based chiral stationary phase Lux i-Amylose-1. Under optimal conditions, the racemic Naproxen was efficiently separated with a resolution factor of 2.33 and a separation factor (alpha) of 1.16. This method can be used for the enantiomeric separation and purity assessment of S-Naproxen, the Active Pharmaceutical Ingredient (API).
Chiral Separation of Lorazepam using a Lux® 5 µm i-Amylose-1 Column
Lorazepam is in a class of drugs called benzodiazepines and is also a medication sold under the brand name Ativan. It initially went on sale in the United States in 1977, and is on the World Health Organization’s (WHO) List of Essential Medicines. Because of this medication’s worldwide significance, it is important to have an enantioselective form of analysis to aid in the detection of dosage and impurities. A simple and robust method was developed for the separation between each Lorazepam enantiomer using a Lux i-Amylose-1 chiral column.
Analytical Options for Cannabis Testing
This product guide presents the analytical options for your laboratory's cannabis testing needs on offer from Phenomenex.
LC-MS/MS Environmental Applications
The world is changing and we need to widen our Environmental Scope. Although analytical techniques and established regulated methods are not easily changed; more complex targets, larger lists, and a variety of sample matrices create a daily challenge for environmental chemists. By using the latest technologies and techniques in HPLC/ UHPLC and Sample Preparation, laboratories and chemists are able to develop better approaches to make their work Faster, Cheaper and Easier. Phenomenex is committed to supporting the industry through a comprehensive product portfolio of Sample Preparation, HPLC/UHPLC, and LC-MS, columns and accessories, along with application and method development services to meet industry needs.
Lux - USP and EP Chiral Column Selection
This application note provides guidance on how to select a Lux Chiral Column for USP and Ph.Eur. (EP) and gives a description of each column.
Novel Approach to Separating Amphetamine Enantiomers from Urine Using Lux® 3 μm AMP
This application note describes an alternative method for quantification of amphetamine enantiomers from urine to off-line derivatization followed by GC/MS or LC/MS. The novel approach utilizes a Gemini® C18 trapping column and Lux 3 μm AMP analytical column to carry out the reversed phase separation of amphetamine and substituted amphetamines without the need for derivatization. This article highlights the benefits of this method over the traditional method, which include greater reliability, greater sample throughput and being less time-consuming.
Webinar Highlights: Achieving Greater UHPLC Performance: Three Innovative Surface Chemistries for Reversed Phase, Size Exclusion and Chiral LC Methods
Discover the benefits of new technology and method development strategies for new techniques
