Chiral Separation of Naproxen by High Performance Liquid Chromatography on Lux® i-Amylose-1
4 Jun 2019This technical note reports the chiral separation of racemic Naproxen using the immobilized polysaccharide-based chiral stationary phase Lux i-Amylose-1. Under optimal conditions, the racemic Naproxen was efficiently separated with a resolution factor of 2.33 and a separation factor (alpha) of 1.16. This method can be used for the enantiomeric separation and purity assessment of S-Naproxen, the Active Pharmaceutical Ingredient (API).
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Lux™ Chiral LC & SFC Columns
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