Chiral Separation of Lorazepam using a Lux® 5 µm i-Amylose-1 Column
4 Jun 2019Lorazepam is in a class of drugs called benzodiazepines and is also a medication sold under the brand name Ativan. It initially went on sale in the United States in 1977, and is on the World Health Organization’s (WHO) List of Essential Medicines. Because of this medication’s worldwide significance, it is important to have an enantioselective form of analysis to aid in the detection of dosage and impurities. A simple and robust method was developed for the separation between each Lorazepam enantiomer using a Lux i-Amylose-1 chiral column.
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Lux™ Chiral LC & SFC Columns
Phenomenex IncPolysaccharide Chiral HPLC and SFC Columns at a Very Affordable Price. Optimize your chiral separation and chiral purification with Lux® polysaccharide chiral HPLC columns. The Lux family of amylose and cellulose chiral selectors provides a variety of complementary selectivities that allow you to screen for the most effective chiral separation under Reversed Phase, Polar Organic, Normal Phase, and SFC conditions. With numerous publications in peer reviewed journals and countless applications being developed, Lux chiral HPLC columns are rapidly becoming the premier choice for simplified chiral purification and chiral separation worldwide. Column Details: Phase: Amylose-2, Cellulose-1,2,3,4 Particle Size: 3, 5, 10, 20 µm Pore Size: 1000 Å Length: 50, 100, 150, 250 mm ID: 2.0, 4.6, 10.0, 21.2, 30.0, 50.0 mm