KINACore Kinase Directed Library

ChemBridge® offers two computationally selected sets of compounds for kinase screening: The KINACore Library, selected from our CORE Library stock, and the KINASet Library, selected from our EXPRESS-Pick™ Collection stock. The libraries are based on pharmacophores generated from compounds active against kinase targets or pharmacophores from the adenosine portion of ATP. The two libraries are non-overlapping, and clients can purchase the full sets or custom-select a subset of compounds from one or both libraries.

ChemBridge® offers small-molecule sets targeted or focused towards specific targets or applications. The targeted and focused libraries originate from both their CORE Library stock and EXPRESS-Pick™ Collection stock of small molecule screening compounds. Clients can custom select/cherry-pick compounds from any of the sets.

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More than 1,500 articles cite the use of ChemBridge® small molecule screening libraries and compounds in a wide variety of research areas using high-throughput screening or focused screening following computer-aided screening. The list below highlights a small sampling of articles, from 2014 to present, that focus on work in cancer research and provides a sample of the different techniques employed and targets explored in hit finding and probe discovery using ChemBridge libraries and compounds.