Products & ReviewLife Sciences

GS Junior System

The power of next-gen sequencing in your hands. The GS Junior System brings the power of 454 Sequencing Systems directly to the laboratory benchtop. Get comprehensive genome coverage with long 400 bp sequencing reads and quickly proceed from DNA to discovery with fast sequencing runs and straightforward data analysis on the attendant computer.GS Junior System Features: Powered by proven technology: Uses GS Junior Titanium…

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Average Rating 3.9

|2Scientists have reviewed this product

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Average Rating 4.0

This machine is rarely used in Germany. There are very little ivd/ce kits available. Plus it has high routine costs.

Review Date: 16 Dec 2013

Average Rating 3.7

Application Area:

Human Genome/HLA GType

I have been using this product for one year and half running almost 40 injections. It’s easy and fast with almost 5 days to get your sequencing results. However, comparing to other companies it’s quite expensive. The automated system is still not sufficient and every step needs to be done manually. In general, it’s a good equipment for short sequencing goals.

Review Date: 21 Mar 2013

The power of next-gen sequencing in your hands.

The GS Junior System brings the power of 454 Sequencing Systems directly to the laboratory benchtop. Get comprehensive genome coverage with long 400 bp sequencing reads and quickly proceed from DNA to discovery with fast sequencing runs and straightforward data analysis on the attendant computer.


GS Junior System Features:

  • Powered by proven technology: Uses GS Junior Titanium chemistry to deliver high-quality, bioinformatics-friendly, long read data
  • Fits in your lab: Small instrument size, along with low entry and operating costs, enables labs with limited budget and infrastructure to take advantage of next gen sequencing
  • Easy to use: Manageable data size allows processing and analysis right on the attendant computer without the need for specialized computing or network infrastructures
  • Point-and-click data analysis: Includes the GS Data Analysis Software for de novo assembly, reference mapping and amplicon variant analysis

Applications:

  • Amplicon Sequencing: Targeted sequencing of 10's - 100's of samples and loci
  • Sequence Capture: Targeted sequencing of custom array regions
  • Whole Genome Sequencing: De novo sequencing and resequencing of microbial organisms (bacteria, fungi, viruses)
  • Metagenomics: Characterization of complex environmental samples; pathogen discovery
  • Transcriptome Sequencing: Full-length sequencing and de novo assembly of transcripts
Application NoteLife Sciences

Screening Cancer Genes Using NimbleGen Sequence Capture Arrays and the GS Junior Sequencing System

This application note by Roche illustrates a method for screening a core set of exons from 75 genes associated with cancer in a single GS Junior sequencing run. Oligo hybridization methods have been shown to effectively enrich for both contiguous and disjoint regions of the genome with much less effort than is required for PCR. DNA from three human cancer cell lines was captured and sequenced. Known variants from the literature were identified along with >900 previously unobserved variants including 30–60 insertions and deletions per sample.

Explore Next Generation Sequencing Possibilities with The GS Junior

This informative video from Roche introduces the conveniently sized bench top GS Junior DNA sequencing machine. This new technology provides an end to end next generation DNA sequencing system, enabling research labs to integrate NGS into everyday lab systems. Long reads of 400 – 500 bp can be obtained with a single run of up to 10 hours generating 35 million high quality bases.

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