Force Biphenyl LC Column
Force LC columns are available with Restek's most popular and highly selective Biphenyl and FluoroPhenyl phases, as well as a general-purpose C18.
Receive your quote directly from the manufacturer.
Great results and lifespan with the Force Columns
Analyzing drugs in urine screens
We love these columns! We updated our method in 2018 and switched from the Raptors to the Force columns and they are wonderful with what we use them for. Their life span has doubled if not tripled and they're a little cheaper than the Raptors. We still use the Raptors for our Oral Fluid method and they run great, but the Force is awesome! We get great results too.
Review Date: 9 Dec 2019 | Restek Corp.
Good unique column
Reaction monitoring and GLP analyses
Good unique column but bleeds a little. Takes a while to equilibrate. Wish it was also available in flash cartridges.
Review Date: 12 Apr 2019 | Restek Corp.
Force Biphenyl LC Column
- Ideal for bioanalytical testing applications like drug and metabolite analyses.
- Heightened selectivity and retention for compounds that are hard to resolve or elute early on C18 and other phenyl chemistries.
- Limits ionization suppression and allows simple, MS-friendly mobile phases.
- Restek’s most popular LC stationary phase.
Restek's Force LC columns give you the power to maximize instrument uptime, increase productivity, and transfer methods across your entire lab, from your trusted-but-aged HPLC to the cutting-edge UHPLC you just plumbed last week. This incredibly rugged and supremely consistent column line represents the culmination of our twenty-plus years in LC dedicated to continually improving our phase chemistries, our lot and lifetime testing, and our bonding and packing procedures.
Key Features:
- Long-lasting and reproducible—maintain stable retention times and peak shapes, even under the stress of elevated UHPLC pressures and rapid cycling.
- Fully scalable between 3 or 5 µm HPLC and 1.8 µm UHPLC—easily transfer and optimize methods without extensive calculations.
- Premium quality ensured by strict manufacturing and QC procedures—Force LC columns are backed by the strength of our 100% Pure Satisfaction guarantee.
Why biphenyl is replacing C18 in HPLC
Tuesday, November 18, at 16:00 GMT | 17:00 CET | 11:00 EST | 8:00 PST
Developing a new HPLC method often follows a familiar routine in many laboratories: select a C18 column, run a few test injections, and hope for sufficient retention and separation. While C18 remains a widely trusted and globally adopted stationary phase, this webinar introduces a fresh perspective on what’s often considered a 'generic' choice.
Join Application Scientist, Samantha Herbick as she explores the retention profiles of various C18 columns, highlighting that not all C18 phases are created equal, and examines the structural modifications permitted within the USP L1 classification.
She will also introduce biphenyl phase and compare it to C18, showcasing how its unique ligand chemistry offers alternative retention mechanisms that can reshape your approach to method development.
Key learning objectives:
- Explore an overview of the retention mechanisms at play with various C18 column types
- Discover how biphenyl columns retain, how they differ from C18, and how you can benefit from these differences
- Uncover the best practices for successful utilization of biphenyl columns in LC methods
- Hear examples of biphenyl chromatography in applied solutions, with contrast against C18 in the same application
Who should attend?
- Analysts, method development specialists, research chemists, lab managers, and anyone interested in LC-MS.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
