Products & ReviewSpectroscopy

DS-11 Series Spectrophotometer / Fluorometer

DeNovixAvailable: Worldwide

DeNovix takes spectrophotometry to a whole new level of performance with the DS-11 Series. This easy-to-use, compact spectrophotometer delivers full spectrum UV-Vis analysis and fluorescence capability, making it ideal for rapid nucleic acid and protein quality control.

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Reviews

Average Rating 4.8

|498Scientists have reviewed this product

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Awesome combination for R n D

 

Average Rating 5.0

Application Area:

Biotechnology and biopharma

Everything looks great. Lots of information on how to use the many applications on device. Also, got the fluorescent meter that attaches to spectrophotometer . Can't wait to do some assays.

Review Date: 30 Jan 2026 | DeNovix

DS-11 is top notch in ease of use and performance.

 

Average Rating 5.0

Application Area:

Quantification of nucleic acids

I have had the DS-11 Spec in my teaching lab for almost 10 years, and it has worked flawlessly the whole time [knock on wood]. I could not be happier with the products ease of use and performance.

Review Date: 30 Jan 2026 | DeNovix

Best piece of equipment in the lab!

 

Average Rating 5.0

Application Area:

Detection of RNA, DNA(ss & ds), Nucleic acid concentration, UV Vis Spectometry

This machine has been a game changer! Have tons of applications in one place makes my testing so much simpler and fast. I am so glad I bought it.

Review Date: 30 Jan 2026 | DeNovix

Solid instrument

 

Average Rating 5.0

Application Area:

Quantification of Nucleic Acids

Product is very effective and easy to use. We had a minor issue in the beginning but was easily solved with good customer support

Review Date: 30 Jan 2026 | DeNovix

Excellent, simple to use!

 

Average Rating 4.0

Application Area:

Plasmid Concentration Measurement

Great system to quickly measure concentration.

Review Date: 29 Dec 2025 | DeNovix

Very fast

 

Average Rating 4.0

Application Area:

Concentration of plasmid measurement

Very fast to be able to measure our plasmid concentration and repeatable!

Review Date: 29 Dec 2025 | DeNovix

Great & convenient equipment—must have

 

Average Rating 5.0

Application Area:

RNA, DNA, and Protein Quantification

DeNovix is a great device. Fast, accurate, and easy to maintain. We have been using it for 5 - 6 years and it has consistently performed well.

Review Date: 29 Dec 2025 | DeNovix

A very trustworthy system.

 

Average Rating 5.0

Application Area:

Biology

On initial startup had a code bug, but was fixed in reliable timing.

Review Date: 29 Dec 2025 | DeNovix

Good product for diagnostics

 

Average Rating 4.0

Application Area:

Molecular biology

Better ease of use, reliable and bit time consuming

Review Date: 13 Dec 2025 | DeNovix

Gives accurate results

 

Average Rating 5.0

Application Area:

Quantification nucleic acid concentration

Product has a lot of functions and provide accurate results for downstream analysis

Review Date: 28 Nov 2025 | DeNovix

DeNovix takes spectrophotometry to a whole new level of performance with the DS-11 Series. This easy-to-use, compact spectrophotometer delivers full spectrum UV-Vis analysis and fluorescence capability, making it ideal for rapid nucleic acid and protein quality control.

World’s Top-Rated 1 µL Spectrophotometer

  • Three Modes in One: 1 µL UV-Vis, Fluorescence, and Cuvette
  • Eliminate Measurement Errors: SmartPath™ Technology Enables Real-Time Optimization of Every Sample in as Little as 2 seconds
  • Widest Dynamic Range:
    • Microvolume UV-Vis: 0.75 - 37,500 ng/µL (dsDNA)
    • Fluorescence: 0.0005 - 4000 ng/µL (dsDNA)
  • Multi-Award Winning: Trusted by Thousands of Researchers Worldwide
  • Maintenance-Free Design: No Recalibration Required
  • Flexible Export and Connectivity: Wi-Fi, USB, Email, Ethernet, and More

Ready to improve your sample quantification? Experience the DS-11 Series Spectrophotometer / Fluorometer in your lab with our Free Trial program, schedule a call with our applications team to discuss your particular application, or Request a Quote to receive pricing information.

Brochures

Product brochuresSeparations

SmartPath technology explained

Discover in this technical note as it demonstrates the ability of a small volume spectrophotometer to produce both accurate and reliable results with the support of DeNovix SmartPath™ technology. Equipped with precise pathlength control, learn how this technology can help keep pathlength within specification to elevate your microvolume spectrophotometer performance.


Product brochuresSpectroscopy

DS-11 Series Brochure

In this brochure, DeNovix demonstrates the capabilities of DeNovix DS-11 Series, the easy-to-use, innovative, and precise spectrophotometer.


Product brochuresSpectroscopy

DeNovix Fluorescence Quantification Assays Brochure

The combination of DeNovix Fluorescence Quantification Kits and DeNovix Fluorometers provide an analytical package that remove the existing limits of fluorescence quantification. DeNovix Assays offer enhanced dynamic range over comparable Qubit® Assays, giving researchers greater flexibility and avoiding the need for repeated dilutions. All assays are designed for selective quantification of dsDNA or RNA in samples that may be contaminated with biomolecules that interfere with UV-Vis quantification methods.

Scientific PosterLife Sciences

Sample quality control: Absorbance vs fluorescence

Explore this comparative breakdown of UV-Vis absorbance and fluorescence to support better decision-making in sample quality control. Gain insights into the unique advantages of each method and discover the range of DeNovix's instrument models designed to enhance the accuracy and efficiency of your quantitation workflows.


Application NoteGeneral Lab

Absorbance and fluorescence quantification for confident sample QC

Master the science of precise biomolecular analysis with DeNovix’s expert guide to absorbance and fluorescence techniques. This eBook explores the strengths of each method, offering practical insights into purity assessment, assay performance, and optimal workflows for nucleic acid and protein quantification. Learn how the DS-11 Series Spectrophotometer/Fluorometer delivers unmatched sensitivity, specificity, and ease of use, all in one compact system.


Scientific PosterSpectroscopy

DS-Series spectrophotometers/fluorometers

Discover how the DS-11 Series spectrophotometers/fluorometers from DeNovix combine 1 µL UV-Vis, cuvette UV-Vis, and fluorescence into one instrument. Explore how the DS-11 Series combines the ease of use, wide dynamic range, and contamination detection of UV-Vis with the enhanced sensitivity and specificity of fluorescence quantification. This flexibility allows the DS-11 Series to excel in a wide range of applications.


Application eBookSpectroscopy

Absorbance & fluorescence: Your guide to quantification & quality control

Fluorescence and UV-vis absorbance are complementary techniques for the quantification and quality control (QC) of samples. Each method has advantages depending on the application and sample being quantified.

This eBook provides a comprehensive guide to absorbance and fluorescence techniques for quantitation and quality assessment of samples, when to implement each method, how to troubleshoot abnormal ratios, and much more.

Download to explore content including:

  • Purity ratios
  • Quality control of dsDNA for NGS
  • Performance data of microvolume nucleic acid
  • dsDNA assay concentration limits
  • RNA assay performance data


Application NoteSpectroscopy

Absorbance and fluorescence quantification with the DS-11 Series Spectrophotometer/Fluorometer

Download this application note to find out more about how the DeNovix® DS-11 Series Spectrophotometer/Fluorometer enables precise absorbance and fluorescence quantification across a wide dynamic range. The dual-mode spectrophotometer is equipped with SmartPath® Technology, which facilitates accurate and reproducible measurements for both cuvette and 1 µL absorbance modes.


Application NoteSpectroscopy

Sample QC: Absorbance or Fluorescence?

The DS-11 FX Series enables both absorbance and fluorescence measurements in one instrument. The combination of absorbance and fluorescence provides greater confidence and accuracy when measuring samples and is a protocol requirement in applications such as Next Generation Sequencing.


Application NoteSpectroscopy

DS-11 Spectrophotometer EasyApps Highlights

Find out about the features that make the DeNovix DS-11 Spectrophotometer a powerful and easy-to-use platform, including common workflow apps, kinetics measurement, and a variety of useful built-in tools.



Application NoteLife Sciences

Accurate and Precise GFP Quantification with DeNovix Fluorometer

Green fluorescent protein (GFP) is widely used in molecular and cell biology as a reporter gene for expression of proteins. GFP is an intrinsically fluorescent protein that is easily detected using a fluorometer or fluorescence microscope. This application note details a method of quantifying the GFP fluorophore using the DeNovix QFX Fluorometer.



Meet the DeNovix DS-11 Series Spectrophotometer / Fluorometer

The DeNovix DS-11 series spectrophotometer / fluorometer combine fluorescence and microvolume absorbance methods in a single, compact instrument. Rapidly quantify nucleic acid and protein samples over seven orders of magnitude, selecting from your choice of fluorescence assays, 1 µL absorbance or cuvettes.


Listening & Innovating: The Secrets of our Success by DeNovix’s CEO

Meet the entrepreneur behind DeNovix Inc. and hear how the life sciences manufacturer uses feedback from scientists to help develop new products that make a real difference to researchers. In this video interview, Fred Kielhorn, CEO and co-founder of DeNovix Inc., reflects on the impact of winning the Reviewers’ Choice Product of the Year Award 2017 for their innovative DS-11 FX+ Spectrophotometer and shares his top tips for setting up your own business.

Discover how easy it is to generate customer reviews with the SelectScience® Reviews Program Toolkit.
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DeNovix DS 11 FX Quick Start Guide

This video guides users on how to analyze samples and export results from DeNovix DS-11 FX Series Spectrophotometers and Fluorometers. Rapidly and accurately quantify dsDNA, RNA and protein samples using only 1uL of sample. The demonstration includes instructions on how to use both the UV-Vis absorbance EasyApps and fluorescence quantification EasyApps. Learn proper techniques for loading and measuring samples as well as how to export your results to email, network printers, USB drives.



Fluorescence Quantification with DeNovix Instruments

Learn the how and when fluorescence quantification can be the better method to quantify biomolecules. Both fluorescence and UV-Vis methods are simple and each has its advantages over the other. This video explains those details and demonstrates fluorescence quantification using DeNovix fluorometers.


Exporting Results from DeNovix Instruments

Learn how easily results can be exported from DeNovix instruments and in the wide variety of formats. Whether you want to export screenshots, raw data or custom formatted exports to destinations such as email, USB, printers, network folders...it's all explained in this video!


DeNovix EasyApps User Accounts

In this video, learn about the DeNovix Accounts app and how you can configure your DeNovix spectrophotometers and fluorometers for a variety of features including password protected accounts, preferred methods, measurement modes and more.


DeNovix Inc. Receives the Reviewers’ Choice Award™ for Life Sciences Product the Year

The 2017 Reviewers’ Choice Award™ for Life Sciences Product the Year was awarded to DeNovix Inc., for its DS-11 FX+ Spectrophotometer / Fluorometer, a product which combines fluorescence and microvolume absorbance methods in a single, compact instrument. Hear Kevin Kelley, Business Director, DeNovix Inc., describe what product reviews mean to them and their customers, in this video filmed following the awards ceremony at AACR 2017.










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