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DeNovix launches new RNA quantification assay

DeNovix

DeNovix Inc. expands its fluorescence quantification range with the introduction of the new DeNovix RNA Assay.

8 Apr 2020
Diane Li
Assistant Editor

Product news

DeNovix Inc., a developer and manufacturer of instrumentation and assays for the life sciences, has introduced a new RNA fluorescence quantification assay. The assay is suitable for multiple platforms including stand-alone fluorometers, plate readers or any DeNovix fluorescence based instrument.

The new DeNovix RNA Assay delivers a greater dynamic range than existing assay technologies that rely on two kits (Broad Range and High Sensitivity), reducing the time and expense of reanalyzing precious RNA samples. The simple ‘mix-and-measure’ assay provides accurate and specific quantification between 250 pg/µL to 1500 ng/µL RNA with sample volumes between 1 and 20µL. The assay’s proprietary chemistry allows quantification of RNA in the presence of dsDNA or other biomolecules that might can interfere with absorbance based techniques.

“Sensitive and specific quantification of RNA is a critical workflow step for many of our customers.” said Fred Kielhorn, CEO of DeNovix. “An RNA assay has been a consistent request from our customers. The new assay solves the frustration of requiring multiple assay kits to perform one routine step. This technology will save customer time and money as well as conserve valuable sample.”

DeNovix RNA assays add to the range of dsDNA assays provided by DeNovix and integrated into DeNovix EasyApps®. The software comes pre-installed on all DS-11 Series Spectrophotometer / Fluorometer instruments and the standalone QFX fluorometer. The assays can also be implemented easily into existing fluorometers and plate readers.

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DeNovix Fluorescence Quantification Assays

DeNovix

DeNovix Fluorescence Assay Kits and Fluorometers provide the greatest sensitivity and widest dynamic range. Selectively and accurately quantify DNA or RNA in the presence of common contaminants such as other nucleic acids or protein.

(3)

DS-11 Series Spectrophotometer / Fluorometer

DeNovix

DeNovix takes spectrophotometry to a whole new level of performance with the DS-11 Series. This easy-to-use, compact spectrophotometer delivers full spectrum UV-Vis analysis and fluorescence capability, making it ideal for rapid nucleic acid and protein quality control.

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Fluorescence SpectroscopyFluorometers and spectrofluorometers (also called fluorescence spectrometers) are used to measure the intensity and wavelength of fluorescent light emitted from a sample after excitation by illumination. Spectrofluorometers utilize monochromators to select the desired wavelengths, whereas filter fluorometers employ a set of filters. Spectrofluorometers for measuring steady-state fluorescence and lifetime fluorescence (or time-resolved fluorescence) are available, as well as fluorescence microscopes and microplate readers. Find the best fluorescence spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Adhesion AssaysCell adhesion assays are used to quantitate attachment and analyze the molecular mechanisms for extracellular matrix adhesion, cell migration and sensitivity to inhibitors. Find the best cell adhesion assay equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.DNA / RNA QuantificationDetection and quantification of nucleic acids is important in molecular biology, cloning, expression, forensics and clinical diagnostics. Nucleic acids can be detected by labeling with colorimetric, fluorescent or radio labels and using in situ hybridization kits to identify specific sequences. Multiple nucleic acids can be detected and quantified at once using RNA / DNA detection beads or RNA / DNA microarrays. Find the best DNA / RNA Quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Fluorescence Based AssayFluorescence based assays are widely used in life science research and high-throughput screening to measure a broad range of cellular activities.Cell Based AssaysCell-based assays use living cells to measure biological responses to various treatments or stimuli. They are essential for drug discovery, toxicology testing, and understanding cellular mechanisms. These assays are used to assess cell viability, proliferation, gene expression, and other cellular activities. Browse our peer-reviewed product directory to find the best cell-based assay tools and reagents, compare products, read customer reviews, and get pricing directly from manufacturers.

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