BioAccord LC-MS System
The First SmartMS-Enabled Biopharma Solution The Waters BioAccord System is an integrated system that simplifies high performance LC-MS biopharmaceutical analysis for every user. An easy-to-use system solution that puts the power to make decisions directly in your hands; a self-calibrating, self-optimizing, self-sufficient tool that equips you with high quality data you can use to tackle the challenges you face every da…
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Very easy to use
Intact Mass and peptide mapping analysis
A great easy to use instrument when working
Review Date: 23 Mar 2023 | Waters
Absolutely very good results
Detection of residual chemical compounds, confirmatory identification of small organic molecules
The LC-MS is a powerful tool for the detection of residual chemical compounds, confirmatory identification of small organic molecules, and confirmation and quantitation of contaminants and adulterants in pharmaceutical and food samples, for example, vanilla. The instrument is very effective when used and achieves high-quality results which are also reproducible plus I gave good ratings for the equipment as it became easy to use after a very good after-sale service and training and it was also affordable to our institution. My work experience was enjoyable. There were very positive benefits and the instrument was easily hyphenated to another instrument like Mass spectrometers. A typical day included collection logging into their computer and get to analyse and peruse the data that I had analysed
Review Date: 15 Nov 2021 | Waters
Small handy and comparatively cheap instrument, gives very good results.
Peptide mapping
Bioaccord LC-MS system is designed specially for peptide mapping analysis. It is fully automated and very easy to use. Good for new learners. This LC-MS is completely fit for GMP application. It's small, handy and a comparatively cheap instrument, still gives comparative results.
Review Date: 16 Jul 2021 | Waters
Great instrument.
Sample analysis
Wonderful presentation.
Review Date: 1 Jul 2021 | Waters
Excellent results.
Analyze different flavonoids in the engineered strains
Precise and efficient within a limited time.
Review Date: 23 Mar 2021 | Waters
Easy handling and absolute results.
Pharmacological testing
Worthy product.
Review Date: 12 Feb 2021 | Waters
A smart MS for analytical labs.
Biosimilars
The BioAccord offers a wide range of analytical methods that are able to characterize biosimilars to evaluate CQAs. The software is excellent as it comprises of analysis, processing and reporting methods. I think in total, this is a very good investment for analytical labs.
Review Date: 10 Feb 2020 | Waters
Powerful instrumentation which simplifies previously time consuming analytical tasks.
Biopharmaceutical analysis
This product greatly simplifies complex MS analyses for the user. It is a robust and reliable system which allows the user to focus on the analysis of the high quality data it generates.
Review Date: 10 Feb 2020 | Waters
Loving this instrument.
Biopharmaceuticals
The equipment greatly enhanced my department's ability to analyze samples and increased throughput.
Review Date: 10 Feb 2020 | Waters
Excellent product! Must have!
Biopharma
This is a must-have for any lab. It streamlined department testing. Sample turn around time has decreased substantially. Great product!
Review Date: 10 Feb 2020 | Waters
The First SmartMS-Enabled Biopharma Solution
The Waters BioAccord System is an integrated system that simplifies high performance LC-MS biopharmaceutical analysis for every user.
An easy-to-use system solution that puts the power to make decisions directly in your hands; a self-calibrating, self-optimizing, self-sufficient tool that equips you with high quality data you can use to tackle the challenges you face every day during biopharmaceutical development.
Brochures
SmartMS-enabled biopharmaceutical solutions
The BioAccord™ System with SmartMS™ provides a new level of user experience through a simple, consistent, automated setup. Find out how the BioAccord™ could simplify your workflow.
Recommended consumable products for a BioAccord System
Recommended consumables and equipment for use with the BioAccord System.
Instrument specifications for the BioAccord LC-MS System
The BioAccord System is a fully integrated solution that simplifies high performance LC-MS analysis for every user. An easy-to-use system that puts the power to make decisions directly in your hands; a self-calibrating, self-optimizing, self-sufficient tool that equips you with high quality data you can use to tackle the challenges you face every day during biopharmaceutical development and manufacturing.
Low adsorption HPLC columns based on MaxPeak high performance surfaces
In this application note, Waters demonstrates how the PREMIER columns, when constructed with MaxPeak Performance Surfaces, provide a means to improve the liquid chromatography analysis of analytes that are sensitive to adsorption on metal surfaces.
Multi-attribute methods for biopharmaceutical analysis
This notebook compiles app notes generated by the Biopharmaceutical Scientific Operations Team at Waters. They illustrate key attribute monitoring workflows that have been developed to improve and streamline MAM analysis of biotherapeutic proteins.
The multi-attribute method: Modernizing biotherapeutic analysis with MAM
Download the latest eBook published by Waters for three fresh perspectives on the capabilities and adoption trends of MAM workflows within the biopharmaceutical industry.
Rapid analysis of lipid nanoparticle components using the BioAccord LC-MS System
This application note describes a simple, rapid, and routine LC-MS method that was developed for the characterization and analysis of lipid nanoparticle (LNP) components using an ACQUITY Premier CSH C18 Column and the BioAccord System.
Analysis of oligonucleotide impurities on the BioAccord System with ACQUITY Premier
This application note demonstrates an automated, compliance-ready LC-MS workflow for purity analysis and intact mass confirmation of extensively modified oligonucleotides and their impurities.
Rapid analysis of synthetic mRNA cap structure using ion-pairing RPLC with the BioAccord LC-MS System
This application note demonstrates a rapid LC-MS method applicable to evaluating the extent of 5’ capping of synthetic mRNA, an important critical quality attribute (CQA) for synthetic mRNAs, using an ACQUITY Premier Oligonucleotide BEH C18 Column couple with a BioAccord LC-MS System.
LC-MS analysis of single guide RNA and impurities
In this application note, discover how you can achieve automated, fast deconvolution of oligonucleotide spectra across the chromatogram. Plus, learn how you can achieve rapid impurity assignments with excellent mass accuracy and relative abundance to support impurity analysis/monitoring.
Establishment of a robust mAb subunit product quality attribute monitoring method suitable for development, process monitoring, and QC release
In this application note, Waters demonstrate the implementation of a subunit MAM method on two additional Tof-based MS systems (BioAccord and Vion) to monitor antibody glycosylation, glycation, oxidation, and sequence variants.
Increasing LC-MS accessibility for streamlined biotherapeutic analysis
Mass spectrometry (MS), once a technology empowering biotherapeutic characterization, is now a fundamental part of biopharma workflows for attribute-based analysis. This attribute monitoring role has application across the breadth of product and process development, and has expanded into manufacturing and quality organizations that have traditionally had limited experience with LC-MS.
Find out how the Waters BioAccord System provides appropriate sensitivity, mass resolution and selectivity for directly analyzing biomolecules in the form of native proteins and protein complexes, denatured proteins, peptides, nucleic acids, and labeled glycans, providing biopharmaceutical organizations with deeper insights across drug development and commercial operations.
The eBook covers the capabilities of the BioAccord LC-MS System across many biopharma-related applications, including:
- Intact mass analysis
- Peptide mapping
- Oligonucleotides
- Compliant-ready MAM workflows
- Antibody-drug conjugates
- AAV capsid proteins
Improved chromatographic analysis of oligonucleotides with ACQUITY PREMIER Oligonucleotide BEH C<sub>18</sub> Columns
This application note suggests the best practices for achieving sensitive oligonucleotide analyses. Waters demonstrates how stainless steel column hardware contributes significantly to non-specific oligonucleotide adsorption.
Clinical diagnostics workflow - Transforming data into better care
In this video, Waters shows how it can help you provide better care by providing clinical LC-MS/MS solutions that you can trust every step of the way.
How to install the BioAccord System from Waters
In this video, watch Arnaud Delobel, R&D Director, Strategy & Innovation, Quality Assistance, and Claire Butré, Protein chemist, Quality Assistance, unbox and install the BioAccord System, where Aurélien Boland, Field Service Engineer, explains each step.
Setting up the BioAccord System: Part 1
Watch this demonstration to see how to setup the BioAccord System, and learn how it is used for routine biopharma analysis.
Scientists’ Choice Awards: Waters BioAccord LC-MS System announced Best New Drug Discovery & Development Product of 2019
Scientists from around the world chose the Waters BioAccord LC-MS System as the Best New Drug Discovery & Development Product of 2019. In this video, Selena Larkin, a Senior Director at Waters Corporation, shares what it means to win this prestigious award, how the system is helping scientists working in biopharmaceuticals, and what to look out for next from Waters.
How the BioAccord LC-MS System Meets Researchers' Needs and Addresses Existing Concerns
In this video, Dr. Henry Shion, Principal Scientist for Waters Corporation, explores how the BioAccord LC-MS System is designed to exceed user expectations surrounding robustness, reproducibility, ease of use, informatics capabilities, maintenance requirements, and size of footprint.
This interview was filmed as part of our coverage of ASMS 2019 in Atlanta, U.S.A. - see other video highlights here >>
Janssen Expert Discusses Automating Biopharmaceutical Characterization Mass Spec Data
In this video, Dr. Andrew Mahan of Janssen describes the opportunities to automate data acquisition and analysis of biopharmaceutical characterization using mass spectrometry. Mahan discusses perspectives on the new BioAccord LC-MS System, from Waters Corporation, including the benefits of an all-in-one simplified system with built-in applications.
This interview was filmed as part of our coverage of ASMS 2019 in Atlanta, U.S.A. - see other video highlights here >>
Principal Development Scientist Discusses Features and Benefits of BioAccord LC-MS System
In this video, Dr. Ruth Wamsley, Principal Development Scientist at Waters Corporation, discusses her role in developing the new easy-to-use BioAccord LC-MS System, where the focus was on offering exceptional usability, minimal downtime, and improved speed and efficiency of laboratory workflows.
This interview was filmed as part of our coverage of ASMS 2019 in Atlanta, U.S.A. - see other video highlights here >>
Screening New Technologies to Improve Throughput, Hands-Off Time, and Data Quality
In this video, Dr. Scott Corley from Boehringer Ingelheim discusses his work in the Process Analytics Group, where his team works to ensure that multi-attribute assays provide them with real-time, high-throughput, and high-quality data. Here, he emphasizes how critical short turnaround times are and explains the need for robust, automated mass spectrometry systems to reduce hands-on time.
Behind the Scenes at Pittcon 2019
SelectScience Editor Lois Manton-O’Byrne shares highlights from the show floor at the 2019 Pittcon conference and expo, including the chance to interview Nobel Prize winner Sir Fraser Stoddart, and witnessing some of the technological innovations unveiled at the event, from leading manufacturers such as Sartorius, Waters, TA Instruments, Bruker and Thermo Fisher Scientific.
New bioseparation tools for RNA analytics
Waters has introduced a comprehensive set of sample preparation enzymes, reagents, and waters_connect software that simplify sequence and modification confirmation of large molecule RNA therapeutics using liquid chromatography-mass spectrometry (LC-MS) analysis
Accelerating science with technology: The hero lab products you can’t live without
To recognize 25 years of accelerating science, we’re highlighting reviews on innovative technologies and your laboratory essentials
Unlocking the potential of the multi-attribute method (MAM): The future of biopharma
New eBooks by Waters Corporation reveal the capabilities, adoption trends, and future of MAM for biotherapeutic analysis
8 drug discovery lab solutions reviewed by our scientists
We’ve highlighted lab product reviews of drug discovery lab solutions that could benefit your workflows and research
A look at 6 top-rated biopharmaceutical products
Find out what scientists are saying about the biopharmaceutical lab products they use
Waters introduces a reliable and automated solution for mass and purity analysis of biomolecules
New Intact Mass software application on waters_connect enables simplified and significantly faster analysis of biomolecules for mass and purity
Compliant, consistent, and transferrable techniques for viral vector characterization and monitoring
Watch this on-demand webinar to discover how compliant techniques for protein characterization can be applied to viral vector modalities
Waters and Sartorius partner to help bioprocess scientists accelerate clone selection and process development
The collaboration aims to accelerate turnaround time for robust data about critical quality and cell culture media attributes by several weeks
Waters and University of Delaware announce bioprocessing innovation partnership
The partnership will focus on developing analytical solutions to better characterize bioprocesses towards improved quality, yields and efficiency
