Establishment of a robust mAb subunit product quality attribute monitoring method suitable for development, process monitoring, and QC release

11 Apr 2021

In this application note, Waters demonstrate the implementation of a subunit MAM method on two additional Tof-based MS systems (BioAccord and Vion) to monitor antibody glycosylation, glycation, oxidation, and sequence variants.

BioAccord LC-MS System

Waters

The First SmartMS-Enabled Biopharma Solution  The Waters BioAccord System is an integrated system that simplifies high performance LC-MS biopharmaceutical analysis for every user. An easy-to-use system solution that puts the power to make decisions directly in your hands; a self-calibrating, self-optimizing, self-sufficient tool that equips you with high quality data you can use to tackle the challenges you face every day during biopharmaceutical development.

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Establishment of a robust mAb subunit product quality attribute monitoring method suitable for development, process monitoring, and QC release