Rapid analysis of lipid nanoparticle components using the BioAccord LC-MS System
30 May 2022This application note describes a simple, rapid, and routine LC-MS method that was developed for the characterization and analysis of lipid nanoparticle (LNP) components using an ACQUITY Premier CSH C18 Column and the BioAccord System.
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BioAccord LC-MS System
WatersThe First SmartMS-Enabled Biopharma Solution The Waters BioAccord System is an integrated system that simplifies high performance LC-MS biopharmaceutical analysis for every user. An easy-to-use system solution that puts the power to make decisions directly in your hands; a self-calibrating, self-optimizing, self-sufficient tool that equips you with high quality data you can use to tackle the challenges you face every day during biopharmaceutical development.
ACQUITY UPLC CSH and XSelect Columns
WatersIntroducing Waters ACQUITY CSH and XSelect Columns - Powered by CSH Technology Waters patent-pending, Charged Surface Hybrid (CSH™) Technology powers the new Waters ACQUITY CSH and XSelect Column families.CSH Technology columns offer separation scientists a wider range of selectivities and greater performance in LC/MS-compatible mobile phases. Waters CSH Technology empowers UPLCand HPLC systems to provide separations with:Widest selectivity rangeSharper peak shapes for ionized compoundsSeamless transferabilityHigher peak capacitiesRapid equilibration after mobile-phase pH changes