Products & ReviewLife Sciences

Antibody Quantification Kits | Protein A & Protein G (SKUs: AK-Ab-001 (Protein A), AK-Ab-005 (Protein G))

AbselionAK-Ab-001 (Protein A), AK-Ab-005 (Protein G)

The Protein A and Protein G Quantification Kits extend the Amperia™ Protein Quantification System for streamlined measurement of antibodies across subclasses and species. Using Fc capture with an inverse-occupancy format, the kits deliver reproducible titres directly from crude or clarified samples, with up to 320 tests per kit.

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Description

Designed for scientists working across antibody discovery, cell line development, and process optimisation, the Protein A and Protein G kits provide ready-to-use solutions for quantitative antibody measurement.

Each kit includes pre-coated sensor strips, assay plates, and reagents for seamless integration with the Amperia™ system. Protein A enables robust IgG quantification across subclasses, while Protein G extends coverage to a broader range of species and isotypes. Both kits use an inverse-occupancy assay format with electrochemical detection, ensuring reliable performance across users, runs, and sample types.

Key Features:

  • Ready-to-use format tailored for the Amperia™ system
  • Fc-based capture with inverse-occupancy detection
  • Up to 320 tests per kit (5 sensor strips, 10 plates included)
  • Compatible with crude harvests and clarified samples
  • Extended subclass and species coverage with Protein G
  • Validated for reproducibility across runs and users

Applications:

  • Antibody titre monitoring in R&D and process development
  • Clone screening and cell line selection
  • Comparative analysis of antibodies across subclasses
  • Bioprocess optimisation
Application NoteLife Sciences

Supporting antibody quantification in biologic development

Monoclonal antibodies (mAbs) remain one of the most widely used therapeutic modalities across oncology, autoimmune diseases, and infectious diseases.

In this application note, Abselion demonstrates the Amperia™ platform, offering a streamlined alternative, enabling consistent, sensor-based mAb quantification directly from cell culture supernatants using an inverse occupancy assay format, with adaptable throughput and simplified setup.

TechTalk: Fast, accurate, accessible quantification across diverse biologics

Friday, January 23 at 16:00 GMT | 17:00 CET | 11:00 EST | 08:00 PST

Quantifying antibodies, AAV capsids, and tagged proteins directly from crude or partially clarified samples remains a common bottleneck in many biologics workflows.

In this 20-minute TechTalk, Dr. Paolo Romele, VP of Science, Abselion will introduce the electrochemical approach used in the Amperia™ benchtop platform, which combines affinity-based capture with Redox Electrochemical Detection (RED) to provide quantitative measurements without relying on optical readouts.

Join this educational and technology-focused session to learn practical examples illustrating how these assays operate across biologics applications.

Key learning objectives:

  • Understand the principles behind affinity-based electrochemical assays using Redox Electrochemical Detection (RED) as implemented in the Amperia™ system.
  • Learn how the three assay formats are applied to antibodies, AAV capsids, and tagged proteins.
  • Review example data demonstrating assay behaviour with directly prepared samples.
  • See how electrochemical detection can complement existing analytical approaches in biologics measurement.

Who should attend?

  • Biotech and pharma scientists working with antibodies, AAV vectors, tagged proteins, protein expression, cell line development, or vector optimization.
  • Research teams in early development focused on process design, screening, assay development, and exploring quantification methods beyond traditional optical assays.

Certificate of attendance
If you attend the live TechTalk, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.

If you view the on-demand TechTalk, you can request a certificate of attendance by emailing editor@selectscience.net.

Product Overview

Links

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