SelectScience InterviewsLife Sciences

Live Cell RNA Detection

23 Apr 2013

In this video Don Weldon tells SelectScience about the new SmartFlare RNA Detection Probes from EMD Millipore. Don explains how live cell RNA detection is now possible, in a single incubation step using inert nanoparticle technology to specifically detect native RNA. He discusses some of the key benefits of this approach compared to existing techniques, such as real-time PCR and demonstrates how the technology works. Interview filmed by SelectScience at AACR 2013.

SmartFlare RNA Detection Probes

Merck

SmartFlare Probes work by recognizing specific native RNA sequences within living cells, therefore there are many possible sequences that you could design to recognize your target of interest. Instead of lysed cells, switch to live cells. And while you’re at it, eliminate sample preparation and transfection steps all together. Live cell RNA detection is now possible, in a single incubation step using inert nanoparticle technology to specifically detect native RNA. And when you’re done, the probes exit the cells allowing you to perform downstream analyses with the same, unperturbed cells. Make the smart change!SmartFlare RNA Detection Probes are fueled by the NanoFlare technology developed by renowned chemist Dr. Chad Mirkin.What's Smart? Detect RNA expression in live cells for real time, physiologically relevant data Eliminate laborious, costly sample preparation Easy analysis on the fluorescent detection platform of your choice Nanoparticle based technology that allows cells to be used for downstream assays

(0)

Other videos from Merck

Links