Direct Compression with Low Dose Micronized Actives - Does This Work?

Advanced technology for excellent tabletting properties Mannitol is a sugar alcohol that is especially suitable as an excipient for advanced, highly active APIs due to its non-hygroscopicity and low content of reducing sugars. Merck Millipore's outstanding, directly compressible mannitol Parteck® M is your best choice – especially if your tableting aims at rapid release of high-dose or low-dose actives.Parteck® M belongs to the Parteck® product family of excipients with unique particle properties developed under the Functional Particle Engineering concept. This concept comprises a number of proprietary technologies which allows specialty excipients with outstanding functionalities especially for the design of solid dosage forms.The extraordinary properties of Parteck® M mannitol allow you to press robust, high-quality tablets directly without the need for additives. This way you achieve compact, more concentrated tablets with fewer process steps and only low compression forces – thereby minimizing wear on your tableting equipment.Parteck® M Benefits: Directly compressible mannitol High compactibility at low compression forces Rapid disintegration High dilution potential EMPROVE® documentation