Uncover new dimensions of isotope ratio analysis with Thermo Scientific Orbitrap MS technology
6 Jun 2025Isotope ratio mass spectrometry (IRMS) is a powerful tool for determining subtle isotopic variations within a sample and works by breaking down complex molecules in simple gases. This technique can provide unique insights however important intramolecular isotopic information is often lost.
Explore a new, comprehensive approach to IRMS using electrospray ionization (ESI). Thermo Scientific™ Orbitrap™ MS technology gives access to a wide range of isotopic information from a variety of polar compounds in liquid samples. In contrast to classical IRMS methods, Thermo Scientific™ Orbitrap Exploris™ Isotope Solutions enable the calculation of isotope ratios directly from the relative abundances of the compounds isotopologues, measured as intact molecular ions.