Solid-Phase Extraction > SPE Plates Products & Reviews

Tecan's suite of microparticulate solid phase extraction (SPE) consumables uses microparticulate sorbents with optimized small flow paths, to ensure greater contact with the analyte molecules. This enables better clean-up of the sample matrix, leading to cleaner sample extracts.Tecan also offers a variety of sorbent chemistries, from state-of-the-art polymer technologies to unique target resins for more complex workflows.

Clean Screen® Xcel Well Plates The Clean Screen Xcel products are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I well plate will extract a wide array of basic drugs including benzodiazepines and opiates.…

A Rapid Solid Phase Extraction (SPE) Solution

The FASt Well Plate is a novel approach to improved sample preparation for LC/MS analysis. The well plate employs a one step process to prepare urine samples for analysis of multiple drugs and metabolites. By quickly and efficiently reducing the amount of unwanted matrix and particulates in the final sample, the analysis can proceed with less chance of matrix suppression and LC column clogging.

The GlycoWorks Product Line was developed and designed to compliment the existing Waters Glycan Application Solution. Concentrating on 2-AB labeled N-Glycan, this sample preparation offering and complimentary standards provides a unique, comprehensive yet versatile solution. The GlycoWorks HILIC uElution Plate is ideal for removing contaminants like salts and detergents from hydrophilic analytes, such as carbohydrates, prior…

The Sirocco™ plates are the most technologically advanced protein precipitation plates in the market and enable high-throughput “in-well” protein precipitation of biological samples without the fear of cloudy filtrates or clogged devices. It also provides optimum performance in faster processing time by reducing steps in ‘in-well’ sample processing and complete recovery of clean filtrate from smaller plasma sample volumes.

The Oasis® uElution plate format combined with the Oasis chemistries allow elution volumes as low as 25uL, eliminating the time consuming evaporation step, producing very clean extracts with a 5 to 10 fold increase in concentration.The Oasis® family of sample extraction products is designed to simplify and improve your sample preparation by combining the right sorbent chemistry, device format and methodology. Achieve robust, s…

Bond Elut 96 Square-well Plates are specially designed to offer superior cleanliness, flow reproducibility, and reliability, ensuring trouble-free, high throughput operation. Conversion of cartridge-based methods to an automation-friendly 96-well plate format has never been easier or faster.

The MonoSpin series is a spin column optimized for rapid preparation of biological samples like blood, serum, and urine. Using silica monoliths, it enables fast separation and high sensitivity. SPE is completed within 10 minutes by centrifugation. Available in Spin, Large, and 96-well formats, it offers high recovery without frits and is ideal for peptides, proteins, drugs, glycans, and organic acids.

MonoSpin Pro Series packs monolithic silica into spin columns and 96-well plates for ultrafast antibody prep. No frits, minimal dead volume. Complete in <10 min at ~2,300×g and elute in just 100 μL with ≥90% IgG recovery (ProA)—competitors often need ≥400 μL for ~65–70%. Choose ProA/ProG for Fc capture or ProL for Fab selectivity; formats include Type S, 96-well, and Large (up to 8 mL).

The Microlute® technology features a robust porous plastic structure that contains chromatographically active media immobilised within uniformly distributed pores.

The Microlute® technology features a robust porous plastic structure that contains chromatographically active media immobilised within uniformly distributed pores.

The Microlute® technology features a robust porous plastic structure that contains chromatographically active media immobilised within uniformly distributed pores.

InertSep Oligo is a solid-phase extraction (SPE) product for oligonucleotide purification in LC/MS workflows. It delivers high recovery, low variability, and full LC/MS compatibility. Formats include 96-well plates—Micro Elution (2 mg/400 µL) and 2 mL square-well (25 mg)—and straight barrel cartridges in multiple sizes for manual or automated high-throughput sample prep.

Meet the InertSep Micro Elution SPE Plate: elongated wells and a high-efficiency 2 mg sorbent bed drive strong retention with just 25–150 µL elution. Skip dry-down, use less solvent, and accelerate LC–MS/MS workflows. Handle 10–100 µL samples with excellent recovery across HLB, MCX/WCX, and MAX/WAX chemistries.

Remove variability and optimize high throughput laboratory workflows. Thermo Scientific™ SOLAµ™Solid Phase Extraction (SPE) Well Plates are designed for bioanalytical and clinical research analysts who require cleaner, highly reproducible, and robust sample extraction using very low sample and solvent volumes in high throughput workflows. SOLAµ Well Plates achieve this due to the unique and award winning innovative frit-less S…

Our HybridSPE ® -PLus plates effectively remove phospholipids and proteins from biological matrices in a simple pass-through method for accurate and reproducible LC-MS analysis. Unlike other phospholipid removal SPE products on the market, the unique retention mechanism of HybridSPE ® allows for separation of even very hydrophobic analytes from phospholipid contaminants.     

Prevent sample failures in bioanalytical workflows

A synthetic, optimized SLE sorbent that improves reproducibility for your extractions when compared to traditional diatomaceous earth SLE sorbents.   

Patent pending HybridSPE – Precipitation (HybridSPE-PPT) technology is a simple and generic sample prep platform designed for the gross level removal of endogenous protein and phospholipid interferences from biological plasma and serum prior to LC-MS or LC-MS/MS analysis. Biological plasma or serum is first subjected to protein precipitation via the addition and mixing of acidified acetonitrile. Precipitated proteins are then…

Functional groups, such as octyl (C8) and octadecyl (C18), can be bonded to the silica surface to provide non polar interactions.  Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte.  The choice of which sorbent is best for a particular method will be influenced by the percent recovery of analyte from the sample matrix and the cleanliness of the resulting chromatography.

Functional groups, such as octyl (C8) and octadecyl (C18), can be bonded to the silica surface to provide non polar interactions.  Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte.  The choice of which sorbent is best for a particular method will be influenced by the percent recovery of analyte from the sample matrix and the cleanliness of the resulting chromatography.

This mixed phase chemistry, in which two primary modes of attraction are present, allows for a more efficient and selective extraction compared to traditional reversed phase techniques.  Neutral and ionized analytes can be simultaneously extracted from a complex mixture and eluted as separate fractions.  A mixed phase sorbent offers the following advantages: Eluting acidic and neutral analytes separately from basic analy…

This chemistry promotes high retention of a wide range of analytes, reducing method development time and facilitating a generic approach to sample preparation.

Functional groups, such as octyl (C8) and octadecyl (C18), can be bonded to the silica surface to provide non polar interactions.  Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte.  The choice of which sorbent is best for a particular method will be influenced by the percent recovery of analyte from the sample matrix and the cleanliness of the resulting chromatography.